etomidate

(redirected from Amidate)

etomidate

 [ĕ-tom´ĭ-dāt]
a sedative and hypnotic, administered intravenously for induction and maintenance of general anesthesia and as a supplement to low-potency anesthetics for maintenance of anesthesia during short operative procedures.

etomidate

/etom·i·date/ (ĕ-tom´ĭ-dāt) a sedative-hypnotic, administered intravenously for the induction and maintenance of anesthesia.

etomidate

[etom′idāt]
a short-acting, hypnotic nonbarbiturate IV agent used for induction of general anesthesia. It has minimal adverse cardiovascular and respiratory effects, thus providing a greater margin of safety in patients with or at risk for heart disease. Adverse effects include transient reduction in adrenal gland cortisol release, pain on injection, and involuntary muscle movements.

etomidate

A general anaesthetic drug. A brand name is Hypnomidate.

etomidate

an intravenous, nonbarbiturate, fast-inducing anesthetic with no analgesic effect. Also causes suppression of adrenal steroidogenesis and may be used in the treatment of hyperadrenocorticism.
References in periodicals archive ?
Amidate Ligands for the oxovanadium(IV) cation: Design, Synthesis, Structure, Spectroscopic and Electrochemical Properties, Inorg.
s Amidate injection, which is indicated for the induction of general anesthesia.
M2 EQUITYBITES-August 7, 2012-Mylan Inc unveils generic FDA approved Amidate Injection for general anesthesia(C)2012 M2 COMMUNICATIONS http://www.
M2 PHARMA-August 7, 2012-Mylan Inc unveils generic FDA approved Amidate Injection for general anesthesia(C)2012 M2 COMMUNICATIONS
Her research focuses on the application of early transition metal amidate complexes as tunable and novel complexes for the catalytic synthesis of amines.
Polyisocyanates can be stabilized by capping a living polymer chain amidate anion with an acyl chloride in the presence of an amine catalyst.
Furthermore, recent experimental and theoretical works described that the electrical properties of such composites are dependent on the concentration, type, and aspect ratio of CNTs [18, 19], as well as their state of dispersion and orientation in the matrix [20], Therefore, properly dispersing and orienting CNTs into polymer substrates has attracted lots of interests, and noncovalent connection of physical adsorption, wrapping, and covalent connection of chemical modification like oxidize and amidate, even additional magnetic and electric fields were employed to align CNTs individually in the matrix [21-24].
Acknowledging the general activity of Group 4 cyclopentadienyl-based catalysts, Schafer's chelating amidate ligand offers variable steric and electronic substituents in the backbone, ultimately enabling her to tune the environment about the metal centre for optimal catalysis.
The reason is that all attempts to amidate PET in the melt resulted so far in crosslinked products.
Food & Drug Administration (FDA) for our novel HIV protease inhibitor GS 9005 and continuing the clinical development of GS 7340, a novel amidate prodrug of tenofovir, based on favorable Phase I/II results.
We continue to focus resources on the development of other promising candidates in our pipeline, including the co-formulation of Viread(R) (tenofovir disoproxil fumarate) and Emtriva(TM) (emtricitabine) into a single fixed-dose combination tablet, and two investigational agents, GS 7340, an amidate prodrug of tenofovir, and GS 9005, a protease inhibitor.
Also during the quarter we submitted marketing applications for adefovir dipivoxil for chronic hepatitis B in both the United States and European Union, and initiated Phase I studies of GS 7340, a novel amidate prodrug of tenofovir for the potential treatment of HIV.