0% Enbrel, Humira, Simponi, (RA)/Crohn's Cimzia, Remicade, Rituxan, Disease Orencia, Actemra Psioriasis Enbrel, Humira, Amevive
, Stelara Multiple Sclerosis 22.
When psoriasis covers large areas of the body, frequent (sometimes weekly) injections of immune-suppressing drugs, such as Amevive
, Enbrel, Humira, or Remicade may be recommended.
13) systemic drugs including Amevive
(alefacept), Raptiva (efalizumab), Enbrel (etanercept) and Remicade (infliximab).
It also will sell the rights to Amevive
, a psoriasis drug approved in 2003 that generated $43 million in sales last year.
Combined sales of the two companies last year approached $4 billion, paced by brisk sales of such products as Avonex, Amevive
, Rituxan and Zevalin.
People coping with chronic psoriasis may benefit from weekly injections of Amevive
(alefacept), a protein that treats the cause of the condition by reducing blood levels of certain immune cells called T-cells.
The non-exclusive licenses will apply to AMEVIVE
(alefacept), currently approved in the United States for moderate-to-severe chronic plaque psoriasis, and other potential products in Biogen's product pipeline.
As for other biologic therapies in this class, the FDA has classified Amevive
as an immunosuppressive because of its effects on T lymphocytes; treatment can increase the risk of malignancies and infections.
These Phase II data show that AMEVIVE
is the first disease-modifying agent for the treatment of psoriasis that has a long duration of effect and is well tolerated.
Biogen (Nasdaq: BGEN) has announced that AMEVIVE
(Recombinantly Engineered LFA-3/IgG1 Human Fusion Protein), its candidate for treatment of moderate-to-severe psoriasis, showed excellent dose response and side-effect profile in a Phase II clinical trial.
the manufacturer of alefacept, has formed the Amevive
Start Assistance Program (866-263-8483) to help patients.
received federal approval for its Amevive
drug, which treats moderate to severe psoriasis.