Amanita phalloides


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Related to Amanita phalloides: Amanita muscaria, Amanita ocreata

Am·a·ni·ta phal·loi·'des

a species of fungus containing poisonous elements, including phalloidin and amanitin, which cause gastroenteritis, hepatic necrosis, and renal necrosis.
Synonym(s): deadly agaric
A mushroom which, along with related species—A bisporigera, A verna, A virosa—is the most common cause of fatal mushroom poisonings
Mechanism The major toxins are amanatins, a series of closely related heat-stable cyclic octapeptides, which inhibit RNA polymerase in liver cells
Management Symptomatic-rehydration, IV glucose, instillation of 100 g of activated charcoal per os, mannitol to prevent oliguria; 50% of late-treated patients die

Amanita phalloides

Toxicology A mushroom which, with related species–A bisporigera, A verna, A virosa are the most common cause of fatal mushroom poisonings Clinical After a 12-hr latency, N&V, abdominal colic, severe watery diarrhea; this is followed by a 24-hr latency period, then–if the amount ingested was significant—by fatal hepatitis and renal failure Management Symptomatic-rehydration, IV glucose, instillation of 100 g of activated charcoal per os, mannitol to prevent oliguria; 50% of late-treated Pts die. See Poisonous mushroom.

Am·a·ni·ta phal·loi·des

(am'ă-nī'tă fă-loy'dēz)
A species of mushroom containing poisonous principles (including phalloidin and amanitin) that cause gastroenteritis, hepatic necrosis, and renal necrosis.
References in periodicals archive ?
In December 2016, fourteen cases of Amanita phalloides poisoning were identified by the California Poison Control System (CPCS) among persons who had consumed foraged wild mushrooms.
Using literature to explore the biogeography and invasion biology of the death cap mushroom Amanita phalloides (Vaill.
Uno de los problemas por los que se retrasa el tratamiento del paciente que ingiere Amanita phalloides es la presentacion tardia de los sintomas de intoxicacion, la cual puede darse entre 6-12 horas posteriores a la ingesta.
Amanita phalloides contains amanitin, inhibiting RNA polymerase II.
About 0.2-0.4 mg of the [alpha]-amanitin can be obtained from 1 g offresh Amanita phalloides.
Hemoperfusion Is Life Saving in Amanita phalloides Intoxication.
Furthermore, patients treated with high doses of silymarin (or its most active component, silybin) shortly after ingesting the deadly toadstool, Amanita phalloides, survive; and multiple studies of silymarin in experimental animal models show it has a broad spectrum of hepatoprotective and antioxidant effects, protecting them against injury from several toxins, including Amanita phalloides, carbon tetrachloride, ethanol, and galactosamine, even when given after exposure (Vogel et al.
Suppose Bellesiles had suggested putting Amanita phalloides into the risotto.
It is in the same family as one of the world's most deadly mushrooms, Amanita Phalloides, or the Death Cap.
In California, there have been several poisonings and some deaths from eating Amanita phalloides, or the death cap mushroom.
When phalloidin (a bicyclic heptapeptide toxin of the toadstool Amanita phalloides) was present in a 2:1 molar excess over actin, we observed a drastic enhancement of the nucleation rate, with a more minor effect on the elongation rate.
Death cap mushrooms (Amanita phalloides) contain one of nature's most potent poisons.