alternative splicing(redirected from Alternative splicings)
different ways of assembling exons to produce different mature mRNAs.
Farlex Partner Medical Dictionary © Farlex 2012
al·ter·na·tive splic·ing(awl-tĕr'nă-tiv splīs'ing)
Different ways of assembling exons to produce different mature mRNAs.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
alternative splicingprocess in which RNA PRIMARY TRANSCRIPTS (containing INTRONS as well as EXONS) of some genes give rise to related, but different, mature mRNAs, by differences in RNA SPLICING so that different combinations of exons assemble. This increases the coding capacity of the GENOME and results in the synthesis of a range of related PROTEINS, called isoforms. Alternative splicing is also called DIFFERENTIAL SPLICING.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005