Alström's syndrome(redirected from Alstrom's syndrome)
an autosomal recessive syndrome usually occuring after age 10, consisting of retinitis pigmentosa with nystagmus and early loss of central vision, deafness, obesity, and diabetes mellitus.
Etymology: Carl Henry Alström, Swedish geneticist, 1907-1993
an inherited disease characterized by multiple system resistance to hormones. Clinical features include retinal degeneration leading to childhood blindness, type 2 diabetes mellitus, infantile obesity, nerve deafness, baldness, hyperuricemia, and hypertriglyceridemia. Males may also have high plasma gonadotropin levels and hypogonadism. The condition is transmitted through an autosomal-recessive gene.