alphavirus

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Al·pha·vi·rus

(al'fă-vī'rŭs),
One of the genera of the family Togaviridae that was formerly classified as part of the "group A" arboviruses and includes the viruses that cause eastern equine, western equine, and Venezuelan encephalitis.

alphavirus

(ăl′fə-vī′rəs)
n.
Any of a genus of single-stranded RNA viruses that infect animals and cause diseases such as chikungunya and Eastern equine encephalitis.

alphavirus

A member of the group-IV Togaviridae, characterised by 70-nm virions surrounding a 40-nm isometric nucleocapsid, which contains a single-stranded linear RNA.

Pathogenic alphaviruses
Eastern, Western and Venezuela equine encephalitis viruses; Sindbis virus; Semliki Forest virus (which may be used as a vector for heterologous gene expression); Ross River; O’Nyong-Nyong virus.
 
Epidemiology
Pathogenic alphaviruses of the Western hemisphere occur primarily in the summer.
 
Clinical findings
Headache, fever, chills, nausea, vomiting, mental confusion, somnolence.
 
Lab
Lymphocytosis and increased protein in CSF.
 
Management
Supportive, intensive nursing care.
 
Sequelae
Neurologic effects (e.g., mental retardation), convulsions, paralysis in 30–70% of survivors.

alphavirus

Group A arbovirus Virology A genus of the family Togaviridae characterized by 50-60 nm virions containing a single-stranded linear RNA Pathogenic alphaviruses Eastern, western, and Venezuela equine encephalitis viruses, Sindbis virus and Semliki Forest viruses–which may be used as vectors for expressing heterologous genes, Ross River, o'nyong-nyong virus Epidemiology Pathogenic alphaviruses of the Western hemisphere occur primarily in the summer Clinical Headache, fever, chills, N&V, mental confusion, somnolence Laboratory Lymphocytosis and ↑ protein in CSF Management Supportive, intensive nursing care Sequelae Neurologic effects–eg, mental retardation, convulsions, paralysis in 30–70% of survivors

Al·pha·vi·rus

(al'fă-vī'rŭs)
One of the genera of the family Togaviridae that was formerly classified as part of the "group A" arboviruses and includes the viruses that cause eastern equine, western equine, and Venezuelan encephalitis.
References in periodicals archive ?
Neurological sequelae resulting from encephalitic alphavirus infection. Front Microbiol.
However, as with other alphavirus infections (i.e., chikungunya [Africa, Asia], o'nyong-nyong [Africa], Ross River [Australia, Oceania], Barmah Forest [Australia], and Sindbis [Africa, Europe, Asia, Australia]), the hallmark of MAYV infection is the highly debilitating arthralgia.
However, alphavirus infections not endemic to Australia are unlikely to be diagnosed serologically because specific assays are generally available only for those viruses known to circulate in Australia.