alphafetoprotein


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alphafetoprotein

A protein synthesized in the fetal liver and intestine and present in fetal blood and in the uterine fluid. Raised levels may indicate that the fetus has SPINA BIFIDA or ANENCEPHALY and further investigation becomes urgent. Alphafetoprotein is also produced by certain malignant tumours and its estimation is sometimes used as a marker for the diagnosis of these tumours or their recurrence.
References in periodicals archive ?
The rate of poor differentiation and alphafetoprotein level above 1000 ng/mL were more common in this group, but based on univariate and multivariate analyses, these factors did not reach statistical significance in predicting MVI on pathology.
Meng et al., "T-cell responses to HLA-A*0201 immunodominant peptides derived from alphafetoprotein in patients with hepatocellular cancer," Clinical Cancer Research, vol.
The possibility of this diagnosis should be entertained especially if the serum alphafetoprotein levels are not elevated.
Ultrasound scan is considered to be standard investigation for obtaining exact information for localization of pregnancy and its relation to surrounding organs.10 In cases where ultrasound is equivocal, MRI may be informative.11,12 Elevated serum alphafetoprotein has also been associated with abdominal pregnancy.13 Diagnostic laparoscopy may also be of value when there is a doubt about pregnancy location.14 In some cases, the diagnosis is not made until laparotomy is performed.
Aflatoxin Exposure Produces Se-rum Alphafetoprotein Elevations and Marked Oval Cell Proliferation in Young Male Pekin Ducklings.
We collected demographic variables (age), diagnostic examination results (imaging studies), tumour markers (alphafetoprotein, beta-human chorionic gonadotropin, lactate dehydrogenase), clinical staging information, treatment information (orchiectomy, chemotherapy, retroperitoneal lymph node dissection) and tumour characteristics (histopathology).
Seller, "Alphafetoprotein in midtrimester Down's syndrome fetal serum," Journal of Medical Genetics, vol.
(4) cancer biomarkers (available for some records): estrogen receptor for breast cancer, acid phosphatase for prostate cancer, alphafetoprotein for testicular cancer, carcinoembryonic antigen (CEA) for colorectal cancer, and carbohydrate antigen (CA-125) for ovarian cancer;
Laboratory tests, including serum alphafetoprotein (aFP) and beta-human chorionic gonadotropin (HCG) levels, were within normal limits.
Kohlwes, "Test characteristics of alphafetoprotein for detecting hepatocellular carcinoma in patients with hepatitis C.