TUBA1A

(redirected from Alpha-tubulin 3)

TUBA1A

A gene on chromosome 12q13.12 that encodes an alpha tubulin, which combines with a beta tubulin to form microtubules, acting as a scaffold to determine cell shape and providing a matrix for cell organelle and vesicle movement via motor proteins.

Molecular pathology
Defects of TUBA1A cause of lissencephaly type 3.
References in periodicals archive ?
Name of Corresponding Homologous gene after BLAST searching cDNA clone genomic clone (% nucleotide sequence identity) STUB1 9-1 Hordeum vulgare alpha-tubulin 3 (90%) accession number AJ132399 SPRP1 10-1,14-1 Zea mays proline-rich protein (84%) accession number Y17332 SAQ1 16-1 Zea mays plasma membrane MIP protein (pip2) (96%) accession number AF131201 SEF1[alpha] 19-1 Zea mays Elongation factor 1[alpha] (93%) accession number U76259