Alpha-interferon


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Alpha-interferon

A natural body substance that now can be made in large quantities and is an effective treatment for some types of viral inflammatory disease, including hepatitis C.
Mentioned in: Hepatitis D
References in periodicals archive ?
In conclusion, EBV-associated LPD in leukemia is a serious complication and extremely rare clinical entity The present case was treated successfully with rituximab and alpha-interferon. Although rituximab therapy seems to be promising in these cases, persistent hypogammaglobulinemia may appear after treatment.
The treatment of renal cell carcinoma with human leukocyte alpha-interferon. J Urol 1983;130:1063-6.
Approval was based on a study of 1,219 adults with chronic hepatitis C infection who had not received alpha-interferon. Treatment responses--defined as undetectable HCV RNA and normalization of alanine transaminase after 24 weeks--were 17% and 24% in those on the 1- and the 1.5-[micro]g doses of PEG-Intron, respectively, vs.
New therapeutic agents are clearly needed to combat this common virus." He continued, "Investigations on the use of alternative medications such as topically applied alpha-interferon, a known antiviral agent, have demonstrated some clinical benefit.
Starting cancer patients on an antidepressant before they begin receiving alpha-interferon markedly reduces the therapy's side effects, Miller and his colleagues now report.
Effect of alpha-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B.
Also last year, a study concluded that the viral protein spurs immune cells called macrophages to release large amounts of alpha-interferon. This chemical seems to suppress other immune cells from making several other compounds that stymie HIV's ability to infect cells.
The use of alpha-interferon and other antiviral strategies to treat liver disease will be explored, with an emphasis on the laboratory's contribution to diagnosis and treatment.
Development of thyroid dysfunction after alpha-interferon treatment of chronic hepatitis C.
Since Omniferon is a naturally occurring alpha-interferon, it is expected to have an improved side-effect profile over recombinant products.
Food and Drug Administration (FDA) last week approved the marketing of bacterially manufactured human alpha-interferon, making it the first member of the interferon family to be commercially available in the United States.
Alpha-interferon treatment may prevent hepatocellular carcinoma in HCV-related liver cirrhosis.