cyclodextrin

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cyclodextrin

(sī-klō-dĕks′trĭn)
A molecule made of linked dextrose subunits that can be used in drug delivery in the body. Cyclodextrins have lipid centers surrounded by water-soluble exteriors. This combination allows fat-soluble medicines to be carried through the bloodstream to lipid-rich organs like the brain.
References in periodicals archive ?
2 pounds each, but once the supplement period began, placebo recipients continued to gain weight, while subjects in the alpha-cyclodextrin group had no significant further weight gain.
10) In addition, patients taking alpha-cyclodextrin had an increase in levels of adiponectin, a hormone that appears to be protective against atherosclerosis, while levels of this beneficial substance fell in the placebo group.
In an attempt to acutely lower post-meal triglycerides, researchers randomly assigned healthy adults to receive either 2 grams alpha-cyclodextrin or a placebo immediately following a commercially prepared high-fat breakfast rich in saturated fat.
2) Subjects were randomly assigned to receive either placebo or two 1 gram tablets of alpha-cyclodextrin with each meal for three months (total 6 grams/day).
But a recent study showed that alpha-cyclodextrin has benefits on body weight and lipid profiles even in healthy, non-obese, nondiabetic people, demonstrating genuine preventive effects.
A group of overweight people (with a body mass index of 25 to 30) were randomly assigned a placebo or 2 grams alpha-cyclodextrin with each meal (6 grams/ day).
3 ounces) of white bread with water or 100 grams of white bread with 10 grams alpha-cyclodextrin in water.
18) It also shows that you can gain control not only of your blood lipids and body weight, but also metabolic and cardiovascular risks, by taking alpha-cyclodextrin before meals.
Similar results were obtained in a study in which the alpha-cyclodextrin (at doses of 2, 5, and 10 grams) was directly mixed with boiled white rice.
A new form of fiber, alpha-cyclodextrin, selectively engulfs dietary fat from the intestine, holding about 9 grams of fat for each gram of the supplement ingested.
And just as importantly, alpha-cyclodextrin, dosed at about 6 grams/day, can reduce high levels of triglyceride, cholesterol, and pro-atherosclerosis lipidcarrying proteins like ApoB, the latter of which is known to be increased by dietary saturated fat.
Studies show that regular use of alpha-cyclodextrin slows weight gain in both obese and non-obese patients, and those both with and without type II diabetes.