cyclodextrin

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cyclodextrin

(sī-klō-dĕks′trĭn)
A molecule made of linked dextrose subunits that can be used in drug delivery in the body. Cyclodextrins have lipid centers surrounded by water-soluble exteriors. This combination allows fat-soluble medicines to be carried through the bloodstream to lipid-rich organs like the brain.
References in periodicals archive ?
For 30 years, Japanese researchers have investigated another benefit of alpha-cyclodextrin. (22) What they discovered is that this compound also selectively absorbs and eliminates bad fats, such as trans fats and saturatedfats, before reaching the bloodstream, while sparing good fats, such as omega-3s, to deliver their benefits.
Researchers designed a controlled human study on the metabolic effects of alpha-cyclodextrin on healthy volunteers.
The corresponding [sup.1]H-NMR spectrum thus consists of relatively broad lines (6 Hz) that could be assigned by comparison with natural alpha-cyclodextrin and/or by recording standard basic COSY experiments [13, 14]: 5.29ppm(d), H1; 3.85(t)H2; 4.43(t)H3; 4.27(m), H4; 4.05(m), H5; 4.3(m)(H6-6').
The goal of the present paper was to investigate the interactions of a preformed cyclosporine complex with a copolymer of alpha-cyclodextrin (ASD) and to study its interactions with membranes by comparison with those of CYSP and POLYA alone.
Studies showed that if alpha-cyclodextrin were taken three times a day during high-fat meals (2 grams per meal), one could engulf as much as 2 ounces of trans fat and saturated fat each day, which represents up to 500 calories of pure fat that never gets absorbed into the bloodstream.
For example, for people who eat two heavy-fat meals a day, (3) 2 grams of alpha-cyclodextrin taken before each of these meals can remove up to 320 calories from the body before absorption.
WACKER will be present at IFT 2013, where the company will showcase CAVAMAXA W6 alpha-cyclodextrin for use in novel icings and coatings for desserts, cakes and baked goods.
Using alpha-cyclodextrin allows to produce new formulations for desserts and baked goods that not only eliminate the need for emulsifiers but mean that they can also be prepared without fat or eggs.
The European Commission has verified a health claim for alpha-cyclodextrin. The EU assessment report confirms that alpha-cyclodextrin can reduce blood sugar peaks following a high-starch meal.
Another candidate product in this segment is alpha-cyclodextrin. The unique structure of this dietary fiber allows it to form a stable, non-digestible complex with dietary fat.
They include a wide range of health claims for probiotics as well as a few other substances, for example, related to vitamin K2 and vascular health, prunes and bowel function, lutein and eye health, soy isoflavones and menopause/bone health, alpha-cyclodextrin and glucose homeostasis, polyphenols from olive and lipid metabolism and lactotripeptides/peptides and the cardiovascular system.
The product consists of alpha lipoic acid (ALA) microencapsulated on a molecular level with alpha-cyclodextrin. The patent pending product is dispersible in water.