Researchers designed a controlled human study on the metabolic effects of alpha-cyclodextrin on healthy volunteers.
The control group that was not taking alpha-cyclodextrin had a dramatic post-meal rise in both glucose and insulin levels.
Alpha-cyclodextrin, at doses of 2, 5, and 10 grams, was directly mixed with boiled white rice.
The study found that alpha-cyclodextrin reduced the glycemic response to standard carbohydrate meals and may be useful for reducing the glycemic response to carbohydrates.
But preventing glucose spikes forms just one part of the overall, longer-term benefits of alpha-cyclodextrin.
Alpha-cyclodextrin can be a helpful strategy in maintaining healthy cholesterol and triglyceride levels while reducing the risk of metabolic syndrome.
Human research demonstrates that alpha-cyclodextrin can be a highly useful component in controlling the negative impact of harmful fats before they enter the bloodstream.
Unlike alpha-cyclodextrin, these medications rely on inhibiting the lipase enzyme that breaks down triglycerides (the major form of dietary fat) into single fatty acid molecules.
Instead of isolating dietary fatty acids from the rest of the intestinal contents the way alpha-cyclodextrin does, these drugs leave triglycerides "loose" in the colon.
Food containing at least five grams of alpha-cyclodextrin per 50 grams of starch in a quantified portion as part of a meal may now carry a label claiming the blood-sugar-lowering effect of the product.
The blood-sugar-lowering effect of alpha-cyclodextrin means that it lowers the glycemic index (GI) of foods, a fact which is important not only to diabetics: such products are digested more slowly and so keep the blood sugar level at a consistently low level.
The food industry uses alpha-cyclodextrin as a water-soluble dietary fiber, e.