alpha cell

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alpha cell

Etymology: Gk, alpha, first letter of the Greek alphabet; L, cella, storeroom
one of a class of cells located in the adenohypophysis or in the pancreatic islets. Alpha cells in the pancreas produce glucagon, which raises the level of glucose in the blood.

alpha cell

A cell of the islets of Langerhans which produces glucagon in response to hypoglycaemia, growth hormone and some amino acids.

alpha cell

1. An enteroendocrine cell that produces glucagon and is found in the pancreatic islets. Synonym: A cell
2. An acidophil of the adenohypophysis (anterior pituitary gland).
See also: cell
References in periodicals archive ?
The glucagonostatic effect of stevioside may be caused by a direct inhibitory action on the glucagon producing alpha-cells or an indirect action via insulin-induced suppression of the glucagon secretion.
This prompted a CT scan, which revealed a distinct mass that appeared to be a pancreatic alpha-cell glucagon-secreting tumor, or glucagonoma.
We aim to: obtain a detailed mechanistic understanding of how nucleotides and drugs regulate KATP channel activity by combining state-of-the-art structural and functional approaches; define how drug therapy affects glucose homeostasis in neonatal diabetes; and explore how activating KATP channel mutations affect glucagon release from pancreatic alpha-cells.
Low doses of bisphenol A and diethylstilbestrol impair Ca2+ signals in pancreatic alpha-cells through a nonclassical membrane estrogen receptor within intact islets of Langerhans.