Alpha-2 agonist

Alpha-2 agonist (alpha-2 adrenergic receptor agonist)

A class of drugs that bind to and stimulate alpha-2 adrenergic receptors, causing responses similar to those of adrenaline and noradrenaline. They inhibit aqueous humor production and a have a wide variety of effects, including dry mouth, fatigue, and drowsiness.
Mentioned in: Glaucoma
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References in periodicals archive ?
Dexmedetomidine is an alpha-2 agonist gaining popularity in neurosurgery due to its unique properties as a sedative, anxiolytic and anaesthetic sparing effects without respiratory depression.
DEXMEDETOMIDINE AS A SOLE ANAESTHETIC AGENT IN NEUROSURGICAL PROCEDURES
Acute iterative bronchospasm and "do not re-intubate" orders: sedation by an alpha-2 agonist combined with noninvasive ventilation.
Building on the Shoulders of Giants: Is the use of Early Spontaneous Ventilation in the Setting of Severe Diffuse Acute Respiratory Distress Syndrome Actually Heretical?/Devlerin Omuzlanndaki Bina: Siddetli Yaygin Akut Solunum Sikintisi Sendromunda Erken Spontan Ventilasyon Kullanimi Gercekten Sira Disi mi?
Dexmedetomidine is an alpha-2 agonist affecting the central nerve system.
Does Patient-Controlled Infraclavicular Perineural Dexmedetomidine Increase the Duration of Postoperative Analgesia?/Hasta Kontrollu Infraklavikular Perinoral Dexmedetomidin Postoperatif Analjezi Suresini Uzatiyor Mu?
Dexmedetomidine is an alpha-2 agonist that can provide sedative and analgesic effects.
Managing procedural pain in a patient taking naltrexone
Dexmedetomidine is a highly selective and potent alpha-2 agonist (alpha 2:alpha 1 = 1620:1) and is 7-10 times more specific for alpha-2 receptors compared to clonidine and has a shorter duration of action.
Comparative evaluation of different doses of intravenous dexmedetomidine during laparoscopic cholecystectomy under general anesthesia
DEX, an alpha-2 agonist, is a widely used sedative in intensive care units.
Dexmedetomidine Attenuates Lipopolysaccharide Induced MCP-1 Expression in Primary Astrocyte
Non availability of u-receptor opioids forces the anesthetists working in some parts of the world to use substitutes like nalbuphine; which is a k-receptor agonist and antagonist at u-opioid1; or tramadol, which acts as a weak u agonist with additional alpha-2 agonist activity and weak inhibitor of norepinephrine and serotonin reuptake2.
A COMPARISON OF EQUIPOTENT DOSES OF TRAMADOL AND NALBUPHINE IN GYNECOLOGICAL LAPAROTOMIES POSTOPERATIVELY
Xylazine, an dose alpha-2 agonist, produces a dose-related degree of sedation and its intravenous injection results in deeper sedation than intramuscular administration (Clarke et al., 2014).
Diagnosis and Retrieval of Pharyngeal Foreign Body in Cattle
In spite of its popularity in the western countries as an alternative therapy for the menopausal vasomotor problems, centrally active alpha-2 agonist clonidine is only marginally more effective than placebo, but considerably less efficient than estrogen [5].
Alternatives of menopausal hormone therapy/Alternative hormonske terapije u menopauzi
Injectable drug company Hospira Inc (NYSE:HSP) revealed on Monday that the US Food and Drug Administration (FDA) has awarded pediatric exclusivity for its alpha-2 agonist Precedex (dexmedetomidine HCl) injection.
Hospira Inc gets US FDA's six months pediatric exclusivity for Precedex injection
Clonidine is an alpha-2 agonist; "agonist" is the opposite of ' "antagonist," meaning it mimics or increases the effects.
New recommendation for fear-based behavior problems: another option for helping dogs cope with storm phobias and other fears
Other authors have also described this biphasic response to the intravenous response of an alpha-2 agonist (22).
Alpha-2B adrenergic receptor mediated hemodynamic profile of etomidate

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