Alpha-1-antitrypsin deficiency: smoking, decline in lung function and implications for therapeutic trials.
The electrophoretic alpha-1-globin pattern of serum alpha-1-antitrypsin deficiency.
American Thoracic Society/European Respiratory Society statement: standards for the diagnosis and management of individuals with alpha-1-antitrypsin
Liver injury in alpha-1-antitrypsin
deficiency: an aggregated protein induced mitochondrial injury.
For many people with rare illnesses such as lysosomal storage disease, hemophilia, Guillain-Barre syndrome, and Alpha-1-antitrypsin
deficiency disease, specialty pharmaceuticals represent their standard of care, keeping symptoms stable and helping to reclaim quality of life.
The cartridges use affinity-purified polyclonal antibodies to remove more than 98 percent of the six most abundant proteins (albumin, immunoglobulin G, immunoglobulin A, alpha-1-antitrypsin
, transferrin and haptoglobin) in human serum and the three most abundant proteins (albumin, immunoglobulin G and transferrin) in mouse serum, with minimal non-specific removal of other proteins.
As published in the March issue of Cell Transplantation, Geron scientists describe protocols that differentiate hESCs into human hepatocytes that express albumin, alpha-1-antitrypsin
, glycogen and toxicity studies to be performed earlier in the drug discovery process, enabling the elimination of toxic compounds before undertaking costly human trials.
a private biotechnology company focused on the development of recombinant alpha-1-antitrypsin
Today the University of Colorado Health Science Center (UC) announced that it had demonstrated in laboratory studies a potentially effective treatment against the AIDS virus using a natural substance called alpha-1-antitrypsin
(AAT) which is a naturally occurring component in human blood.