alloxan

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al·lox·an

(ă-loks'-an),
An oxidation product of uric acid, 2,4,5,6-pyrimidinetetrone; administration to experimental animals causes hypoglycemia resulting from insulin liberation, followed by hyperglycemia resulting from destruction of the islets of Langerhans (alloxan diabetes).

alloxan

/al·lox·an/ (ah-lok´san) an oxidized product of uric acid that tends to destroy the islet cells of the pancreas, thus producing diabetes (alloxan diabetes).

alloxan

[əlok′san]
an oxidation product of uric acid that is found in the human intestine in diarrhea. Alloxan has been used to produce diabetes in experimental animals by destroying the insulin-secreting islet cells of the pancreas.

alloxan

An oxygenated pyrimidine derivative, which is a toxic glucose analogue that induces experimental diabetes by selectively destroying pancreatic beta cells by superoxide production.

al·lox·an

(AX) (ă-loks'an)
An oxidation product of uric acid.

alloxan (əlok´san),

n a substance, mesoxalyl urea, capable of producing experimental diabetes by destroying the islet cells of the pancreas.

alloxan

an oxidized product of uric acid which destroys β cells of the islets of Langerhans in the pancreas. It has been used in experimental studies of diabetes mellitus and in the treatment of insulinomas in dogs.