alloxan

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al·lox·an

(ă-loks'-an),
An oxidation product of uric acid, 2,4,5,6-pyrimidinetetrone; administration to experimental animals causes hypoglycemia resulting from insulin liberation, followed by hyperglycemia resulting from destruction of the islets of Langerhans (alloxan diabetes).

alloxan

An oxygenated pyrimidine derivative, which is a toxic glucose analogue that induces experimental diabetes by selectively destroying pancreatic beta cells by superoxide production.

al·lox·an

(AX) (ă-loks'an)
An oxidation product of uric acid.
References in periodicals archive ?
The results of the experiments showed that alloxane diabetes is characterized by significant insulin insufficiency, which is confirmed by data of the control group.