allosteric control


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allosteric control

The ability of an interaction at one site on a molecule to influence the activity of another site.
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References in periodicals archive ?
Thirdly, this mechanism of allosteric control over enzyme specificity also pointed out that the structural factors that govern substrate recognition by the enzyme active centre could not be presented by simple additive models.
The oxygen binding affinity of natural human hemoglobin is too high when it is free in the blood stream (not contained within erythrocytes) because of a lack of allosteric control. The tetrameric protein also dissociates when free in the blood, allowing it to move out of the blood vessels into other tissues reducing its efficacy as an oxygen carrier and creating problems with normal kidney function.