alloimmunization

al·lo·im·mu·ni·za·tion

(al-lō'im-myū'nī-zā'shŭn),
Immunization against a non-self protein, as occurs in patients receiving transfusions.

alloimmunization

/al·lo·im·mu·ni·za·tion/ (-im″u-nĭ-za´shun) an immune response generated in an individual or strain of one species by an alloantigen from a different individual or strain of the same species.

al·lo·im·mu·ni·za·tion

(al-lō'im-myū'nī-zā'shŭn)
Immunization against a non-self protein, as occurs in patients receiving transfusions.

alloimmunization

development of antibodies in response to alloantigens; antigens derived from a genetically dissimilar animal of the same species. See also alloantigen.
alloimmunization of pregnancy
sensitization of the dam against fetal red blood cell antigens that leak into the maternal circulation across the placenta or during parturition is uncommon except in the mare and sow where it gives rise to alloimmune hemolytic anemia of the newborn.
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References in periodicals archive ?
20) In some instances, such as in patients with GT, alloimmunization to platelet antigens occurs, and hemostatic support has to be provided with activated clotting factor concentrates.
Diagnostic considerations with inherited platelet disorder testing: This month's CE is comprised of two articles
In Rh-D alloimmunization newborns were often severely affected, unstable at birth, necessitated multiple exchange transfusions; thereby associated with extensive morbidity and mortality.
CLINICAL CHARACTERISTICS AND MANAGEMENT OF Rh-D HAEMOLYTIC DISEASE OF NEWBORN
Anti-E alloimmunization in pregnancy: Management dilemmas.
Hyperbilirubinemia due to minor blood group (anti-E) incompatibility in a newborn: a case report
For example, despite matching the ABO blood group antigens during red blood cell (RBC) transfusion, up to 45 percent of chronically transfused patients, such as those with sickle cell disease or thalassemia, develop antibodies to mismatched minor antigens on transfused RBCs; this process is known as alloimmunization.
United States : Modulating dendritic cell movement in spleen could prevent life-threatening immune response in transfusion patients
In the case of platelet transfusions (in patients less than 45 kg), alloimmunization shall be avoided, respecting the ABO platelet group (Grade D, Level 4).
Recomendaciones basadas en la evidencia de terapia transfusional en el paciente oncologico en pediatria
Noninvasive diagnosis by Doppler ultrasonography of fetal anemia due to maternal red-cell alloimmunization.
Sindrome de evans y embarazo en la adolescencia: reporte de un caso y revision de la literatura
1) Rh alloimmunization in pregnancy develops when the maternal red blood cells (RBCs) lacking the Rh antigen (RhD negative) are exposed to RhD positive RBCs through the placenta leading to the activation of the maternal immune system.
Red cell alloimmunization to rhesus antigen among pregnant women attending a tertiary care hospital in Oman
Alloimmunization to human leukocyte antigen (HLA) and/or platelet-specific antigens (HPA) is included in this category.
Absolute platelet refractoriness associated with HLA antibodies: A case report
Consequently, it is highly difficult to find a donor with compatible organs because of the above alloimmunization (RODEY, 2003).
Analysis of platelet eluate for the elucidation of sensitization to HLA in kidney transplant candidate/Analise do eluato de plaqueta para a elucidacao da sensibilizacao ao HLA em um candidato ao transplante de rim
Characterization of Red Blood Cells Alloimmunization at Hospital Universitario del Valle between 2011 and 2013
Caracterizacion de la aloinmunizacion eritrocitaria en el Hospital Universitario del Valle entre 2011 y 2013
The rate of alloimmunization is variable and depends on the frequency of the antigens in the population and on their immunogenicity.
A neonatal agranulocytosis
Key Words: Beta Thalassaemia Major Multiple blood transfusions Alloimmunization.
FREQUENCY OF RED CELL ALLOANTIBODIES AND AUTOANTIBODIES IN THALASSEMIA MAJOR CHILDREN

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