De novo Produced Anti-HLA Antibodies Relation To Alloimmunity
in Patients with Chronic Renal Failure.
and tolerance in corneal transplantation," The Journal of Immunology, vol.
In addition, it was also shown that the presence of allospecific Tregs in graft recipients primarily suppressed the induction of alloimmunity
in the regional draining lymph nodes rather than suppressing the effector phase of the immune response in the periphery .
Antoine Toubert, Head, Alloimmunity
, Autoimmunity, Transplantation, INSERM
In this review, we focus on the migration and homing of the two most critical T cell subsets that are involved in graft alloimmunity
, effector T cells and regulatory T cells, with an emphasis on the chemokines and adhesion molecules involved in the migration of these cells to the draining lymphoid tissues and the graft site.
The alloimmune hypothesis has been confirmed by studies showing the involvement of complement in the pathogenesis of hepatocyte injury, which could result only from maternal alloimmunity
Goldstein, "Toll-like receptors and other links between innate and acquired alloimmunity
," Current Opinion in Immunology, vol.
Due to an inadequate response to platelet transfusions, as shown by corrected count increments (CCI) at 24 hours of 760 platelets x [m.sup.2]/[micro]L on days 3 and 4, and a CCI of <1000 platelets x [m.sup.2]/[micro]L at 1 hour on day 5, a platelet refractory panel was requested to evaluate antibody mediated alloimmunity
as a cause of platelet refractoriness.
Cellular aspects of alloimmunity
and other responses in the gorgonian Swiftia exserta.
Thus, MHC-I upregulation should be specific to tolerance rather than the results of alloimmunity
. We have known that the alterations in MHCI expression play a crucial step in immune evasion of cancer or virus-infected cells through the regulation of adaptive T-cell cytotoxicity  and innate NK cell function .
Experiments using a heterotopic tracheal transplantation model demonstrate that alloimmunity
is required .
(9) In addition, previous reports have indicated that immunological problems involving autoimmunity, (10,11) alloimmunity
(12) and embryotoxic factors (13) are associated with EPL.