allele frequency


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Related to allele frequency: Genotype frequency

allele frequency

A term used in population genetics for the number of copies of a particular allele divided by the number of copies of all alleles at that specific genetic locus in a population of interest. Allele frequency is a measure of a population’s genetic diversity: the higher the allele frequency, the greater the population’s consanguinity.
Allele frequencyclick for a larger image
Fig. 23 Allele frequency . Calculation of allele frequency from genotype frequency.

allele frequency

or

gene frequency

the proportion of a particular ALLELE of a gene in a population, relative to other alleles of the same gene. For example, if a gene has two alleles, A and a , and the frequency of A is 0.6, then the frequency of a will be 1.0 - 0.6 = 0.4. The allele frequency can be calculated from the GENOTYPE FREQUENCY; See Fig. 23 .
References in periodicals archive ?
Table-3: Genotype and Allele Frequency Distribution of the study subjects.
Description and power analysis of two tests for detecting recent population bottlenecks from allele frequency data.
In contrast, the allele frequency results for the c.501A>G (p.Pro167Pro) SNP in exon 3 showed a non-significant association with plumage color (Table 3).
Allele frequency of 16 EST-SSR primers evaluated in nine recurrent selection cycles (C0-C8) in popcorn population UENF14.
Our analysis identified 31 HLA-A alleles in influenza patients (INF-P) and 38 in asymptomatic healthy contacts (INF-C) out of which 7 of the alleles in the INF-P group showed an allele frequency (AF) higher than 6%; the most common were A * 02:01:01 (24.6%), A * 68:01:02 (11.6%), A* 24:02:01 (7.9%), A* 03:01:01 (7.6%), A* 31:01:02 (7.2%), and A * 01:01:01 (6.5%).
The allele frequency differences between ethnic groups most likely results from evolutionary process and population genetic behaviour.
In the AD group, C allele frequency of the TLR2 R753Q SNP was 99.29%> and T allele frequency was 0.71%>; in the control group, C and T allele frequencies for the TLR2 R753Q SNP were 97.83%> and 2.17%, respectively.
For allele frequency, the result was similar with the genotype analysis that better metformin efficacy was found in the T allele.
While there is no significant difference for the PECAM-1 (+373 C/G) in allele frequency between CAL in the Kawasaki disease group (+373 C/G: [chi square] = 5.19, P = 0.0745).
Results: Compared with healthy controls, the allele frequency of HLA-DRB1*0701 was increased in the Uyghur patients (P = 0.008) but not in the Han patients (P = 0.869).
Polymorphisms Allele Frequency OR Sample size Power * (%) (Cases/controls) (%) rs320 G 39 2.0 182/182 86.0 133/269 89.3 rs285 T 49 2.0 162/162 86.0 133/269 92.5 rs328 G 15 0.5 244/244 86.0 133/269 78.8 * Allele frequency taking from reference 7 Table 2.