allele frequency

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allele frequency

A term used in population genetics for the number of copies of a particular allele divided by the number of copies of all alleles at that specific genetic locus in a population of interest. Allele frequency is a measure of a population’s genetic diversity: the higher the allele frequency, the greater the population’s consanguinity.
Allele frequencyclick for a larger image
Fig. 23 Allele frequency . Calculation of allele frequency from genotype frequency.

allele frequency

or

gene frequency

the proportion of a particular ALLELE of a gene in a population, relative to other alleles of the same gene. For example, if a gene has two alleles, A and a , and the frequency of A is 0.6, then the frequency of a will be 1.0 - 0.6 = 0.4. The allele frequency can be calculated from the GENOTYPE FREQUENCY; See Fig. 23 .
References in periodicals archive ?
However, the minor allele frequencies at various SNPs are observed to be higher in the group of the local population.
Previously, a few studies have reported that there was no significant difference in vaspin levels between normal pregnant females and females with GDM.3,15 Yet, a study found that lower levels of vaspin were a risk factor for the development of T2DM.13 The current study did not find any significant difference between the two groups regarding genotype distribution as well as allele frequencies (p>0.05), suggesting that this may not be related to GDM.
Forensic parameters and allele frequencies of 15 autosomal STR loci (D8S1179, D21S11, D7S820, CSF-IPO, D3S1358, THOl, D13S17, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA) are shown in table 1.
Molecular diversity measures showed little difference in values across replicate datasets; therefore, we report results from one dataset with sampling from historical allele frequencies and one dataset with sampling from this study's allele frequencies.
The genotype and allele frequencies of the identified indel and SNPs in exons of MITF from four duck populations categorized into two groups based on plumage color (white and black or mixed) are shown in Table 3.
Comparing the outputs of this study with the results of the studies that were obtained from native sheep breeds of Turkey showed that the M and N allele frequencies were found higher and lower respectively from Karacabey Merino (80.0 and 19.9), Chios (34.5 and 65.5) (Yilmaz et al, 2014 (b)), Karya (54.4 and 45.6), Cine Capari (73.7 and 26.3) (Ata and Cemal, 2008) and Karakul (73.3 and 26.7) (Avanus, 2015) sheep breeds.
Although SNPs in TLR2, TLR4, PGR, and IL-6 did not exhibit statistically significant differences in genotype or allele frequencies between study and control groups, they had high values of ORs (>1.97) for either mutant allele or genotype.
Conversely, there were no significant differences in allele frequencies between the two subgroups.