retinal

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retinal

 [ret´ĭ-nal]
1. pertaining to the retina.
2. the aldehyde of retinol, having vitamin A activity. One isomer (11-cis-retinal) combines with opsin in the retinal rods (scotopsin) to form rhodopsin (visual purple); another, all-trans-retinal, or visual yellow, results from the bleaching of rhodopsin by light, in which the 11-cis form is converted to the all-trans form. Retinal also combines with opsins in the retinal cones to form the three pigments responsible for color vision.

ret·i·nal

(ret'i-năl),
1. Relating to the retina.
2. Retinaldehyde, most commonly referring to the all-trans form; participates in the visual process; 11-cis-retinal binds with an opsin to form iodopsin or rhodopsin; light causes the formation of all-trans-retinal, which dissociates from the protein.

retinal 1

(rĕt′n-ăl′)
adj.
Of or relating to the retina of the eye.

retinal 2

(rĕt′n-ăl′, -ôl′)
n.
Either of two chromophores that are aldehydes of vitamin A1 and vitamin A2 and that bind covalently with an opsin protein to form rhodopsin or porphyropsin. Also called retinene.

retinal

adjective Referring to the retina noun 11-cis-retinal, vitamin A aldehyde A retinal pigment that absorbs visible light at 400-600 nm, resulting in an isomeric transition of the 11-cis-retinal moiety to a trans-retinal conformation causing a G protein-mediated depolarization event

ret·i·nal

(ret'i-năl)
1. Relating to the retina.
2. Retinaldehyde; most commonly referring to the all-trans form.

retinal

The aldehyde found in visual pigments, such as visual purple. Also known as retinaldehyde.

retinal 

1. Pertaining to the retina.
2. See rhodopsin.
References in periodicals archive ?
Initially, we wanted to mutate all lysines to glycine, but all attempts to convert the "AAG" triplet of lysine 113 in Air-AAR1-Like[DELTA]58 to "GGG" failed, and we decided to mutate it to alanine, "GCG." The mutants were tested with the chromophore that gave the best result for each of the two GCPRs: 11-cis retinal for Air-CCAPR1-Like[DELTA]105 and all-trans retinal for Air-AAR1-Like[DELTA]58.
Surprisingly, both proteins became photosensitive when incubated with 11-cis retinal and all-trans retinal (Fig.
Nevertheless, the circumstantial evidence that we provide for Air-AAR1-Like and Air-CCAPR1-Like (i.e., expression in eyes and/or light-sensitive mantle), combined with the light sensitivity after incubation with 11-cis retinal and all-trans retinal and loss of photosensitivity after removal of key lysines, points toward a putative light sensitivity of these two GPCRs.