ALK

(redirected from Alkes)

ALK

Abbreviation for:
activin-like kinase
anaplastic lymphoma kinase, see there

Genetics
A gene on 2p23 that encodes an orphan receptor with tyrosine kinase activity belonging to the insulin receptor superfamily, which plays an important role in brain development.

Molecular pathology
ALK is amplified, mutated and rearranged in various cancers, including anaplastic large cell lymphomas, neuroblastoma and non-small cell lung cancer. The most common genetic alterations seen in ALK malfunction are chromosomal rearrangements resulting in multiple fusion genes, including ALK/EML4, ALK/RANBP2 and ALK/ATIC (all on chromosome 2); ALK/TFG (on chromosome 3); ALK/NPM1 and ALK/SQSTM1 (both on chromosome 5); ALK/KIF5B (on chromosome 10); ALK/CLTC (on chromosome 17); ALK/TPM4 (on chromosome 19); and ALK/MSN (on X chromosome).
References in periodicals archive ?
Tenders are invited for Supply of different materials for construction of cc road with earth work from alkes bewa house to erfan ali house within malior-ii gp under harishchandrapur-ii dev.
Commenting on these results, Alkes Price from the Harvard School of Public Health noted that because so many regions are implicated, there is the concern that "GWAS will ultimately implicate the entire genome, becoming uninformative.
Madison, WI, USA) by using primers ALKES 1 and ALK-ER (2).
A Navy veteran of World War II, he served in the Pacific Theater as Lieutenant Commander and Supply Officer of the Attack Transport USS Alkes.
Tenders are invited for plain cement concrete road repairing from kamartor alkes ali house to majid ali house at kamartor-06 sansad
Jenny Cao-Nicole Alkes, 6-4, 2-6, 10-6; Liza Welch-Chloe Newell d.
Nhi Ho, 6-4, 2-6, 6-3; Jenny Cao-Nicole Alkes (S) d.
Stephanie Guerrero, 6-0, 6-1; Jenny Cao-Nicole Alkes (D) d.
Jenny Cao-Nicole Alkes, 6-4, 7-6, (7-5); Jackie Forson-Lisa Gitaw (S) d.
2 singles, while Iva Hoxha and Nicole Alkes won at second doubles for South.
Doubles winners were the teams of Ivy Jones-Sabrina Maliqi and Iva Hoxha-Nicole Alkes.
Second Honors: Linda Adubofour dufie, Nicole Alkes, Bernice Appiah, Andrea Aybar, Krystal Bond, Selena Bui, Xiomara Carrasquillo, Gabriel Castanon Meneses, Alex Cobos, Sara Dyson, Demek Edmonds, Karl Enriquez, Claudio Eshun, Jose Feliciano, Gankaris Francisco, Cierra Howell, Saman Jabbar, Victoria Jablonski, Jeremy Leblanc, Sabrina Maliqi, Cheyenne Mcgibbon, Shayla Monteiro, Jimary Navarro Ortiz, Samantha Nedoroscik, Cindy Ngo, Isabella Nguyen, William Nguyen, Yen Nguyen, Elizabeth Oluokun, Marshall Paye, Bryan Rodriguez, Veronica Santiago, Jessica Sawicki, Olivia Sellers, Evelina Smith, Konstantinos Tekelis, Henry Thach, Thao My Truong and Huy Vo.