On the other hand, the drugs that went off patent from 1983 through 1986 were mostly declining products, such as Aldomet
, Diabinase and Valium.
Amoxicillin * Amoxil, Biomox, Polymox, Trimox, Wymox Cephalexin * Biocef, Keflex Celecoxib * Celebrex Diclofenac/Misoprostol * Arthrotec Ipratropium * Atrovent Labetalol * Trandate Methyldopa * Aldomet
Naproxen * Aleve, Anaprox, Naprosyn Nitrofurantoin * Furadantin, Macrobid, Macrodantin Rofecoxib * Vioxx Tiotropium * Spiriva Tolmetin * Tolectin Triamcinalone * Aristocort, Atolone, Kenacort Sulfamethoxazole/Trimethoprim * Bactrim, Cotrim, Septra, Sulfatrim Sulfisoxazole * Gantrisin
, Apo-Methyldopa, Dopamet, Novomedopa), rilmenidine (e.
While the original Beers list consisted of 23 inappropriate drugs, the Harvard paper lays claim to only 20, omitting the three antihypertensives, Inderal (propranolol), Aldomet
(methyldopa), and Serpasil (reserpine), which they determined were too controversial.
Subsequently, Merck discovered a series of products including HYDRODIURIL, ALDOMET
, MODURETIC, RENITEC, PRINIVIL and, most recently, developed COZAAR and HYZAAR(a) in a collaboration with DuPont.