Color changes were also observed as the reaction evolved, which could be attributed to the aldimine
binding reactions (CH = N) that occur when an aldehyde group (-CHO) reacts with an amino group during the crosslinking process.
In the catalysis of PLP-dependent enzymes, the transaldimination reaction is strictly conserved and happens at least two times in forward and reverse directions: the forward reaction is from the internal aldimine
to the external aldimine
and the reverse reaction is vice versa (Scheme 1).
Hydroamination of alkyne 2 with amine 6 yields the aldimine
Dnyanpeeth, "Synthesis and pharmacological activities of 4-carboxaldehyde and its aldimines
derivatives," Asian Journal of Chemistry, vol.
(16.) Subramania, A, Kalyana Sundaram, NT, Sathiya Priya, R, Saminathan, K, Muralidharan, VS, Vasudevan, T, "Aldimines
Effective Corrosion Inhibitors for Mild Steel in Hydrochloric Acid Solution." J.
Baruah, "Participation of self-generated polyaniline support in copper(II) catalysed oxidative reaction of phenyl aldimines
," Journal of Molecular Catalysis A, vol.
Choudary, "Synthesis of a-amino nitriles through Strecker reaction of aldimines
and ketoimines by using nanocrystalline magnesium oxide," Tetrahedron, vol.
Imines , both aldimines
and ketimines due to presence of carbon-nitrogen bond in their molecules, provides a potential site for chemical [12-13] as well as biological [14-15] activity, but very less work has been carried out on synthesis of [alpha],[beta]-unsaturated ketimines.
In addition, cure rates can be lowered by utilizing blocked NHs (i.e., aldimines
and ketimines) that become active upon reacting with atmospheric moisture and/or formulating with ASP-based secondary diamines.
The aim of the present work was to fill this gap and investigate the pinacol coupling of aldimines
in the presence of mischmetall (Ce and La), Zn-Cu couple, and Dewarda alloy (50% Cu, 5% Zn, 45% Al).