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Related to Aldehyde lyases: Isomerases, Ligases


1. Generic term for aldehyde-lyase.
2. Name sometimes applied to fructose-1,6-bisphosphate aldolase.


Any of a class of enzymes that reversibly catalyze the cleavage of carbon-carbon bonds, especially the cleavage of sugars into three-carbon fragments during glycolysis.


Clinical chemistry A serum enzyme that cleaves fructose 1,6-diphosphate to dihydroxyacetone phosphate and glyceraldehyde-3-phosphate in the muscles to produce energy; aldolase is distributed in all tissues and ↑ in skeletal muscle disease or injury, metastatic CA, CML, megaloblastic anemia, hemolytic anemia, or infarction; it is measured in suspected myopathies, as the intensity of ↑ reflects the severity of disease; aldolase may also be ↑ early in Pts who later develop muscular dystrophy and can also be used to monitor steroid therapy in inflammatory myopathies Ref range 3.1-7.5 U/L; aldolase is ↑ in Duchenne's muscular dystrophy, dermatomyositis, polymyositis, trichinosis


An enzyme, found primarily in the muscle, that helps convert sugar into energy.
Mentioned in: Aldolase Test
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