alcohol dehydrogenase

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Related to Alcohol metabolism: alcohol dehydrogenase

al·co·hol de·hy·dro·gen·ase (ADH),

(al'kŏ-hol dē-hi-droj'e-nās),
An oxidoreductase that reversibly converts an alcohol to an aldehyde (or ketone) with NAD+ as the hydride acceptor; for example, ethanol + NAD+ ⇄ acetaldehyde + NADH.
See also: alcohol dehydrogenase (acceptor), alcohol dehydrogenase (NADP+).

alcohol dehydrogenase

/al·co·hol de·hy·dro·gen·ase/ (ADH) (de-hi´dro-jen-ās) an enzyme that catalyzes the reversible oxidation of primary or secondary alcohols to aldehydes; the reaction is the first step in the metabolism of alcohols by the liver.

alcohol dehydrogenase

Any of a class of enzymes that catalyze the oxidation of alcohols to aldehydes or ketones.

al·co·hol de·hy·dro·gen·ase

(ADH) (al'kŏ-hol dē-hī-droj'en-ās)
An oxidoreductase that reversibly converts an alcohol to an aldehyde (or ketone) with NAD+ as the H acceptor. For example, ethanol + NAD+↔ acetaldehyde+ NADH. Plays an important role in alcoholism.


an enzyme that mobilizes the hydrogen of a substrate so that it can pass to a hydrogen acceptor, such as NAD+ or FAD+.

alcohol dehydrogenase
dimeric enzyme protein of the liver catalyzing the NAD+-linked dehydrogenation of ethanol to acetaldehyde.
glucose-6-phosphate dehydrogenase
see glucose-6-phosphate dehydrogenase.
glutamate dehydrogenase (GD), glutamic dehydrogenase
an enzyme that catalyzes the reversible reaction of glutamic acid into 2-oxoglutaric acid and ammonia. High concentrations occur in the liver of sheep, cattle, horses and dogs. Serum levels are useful in detecting hepatocellular damage in ruminants.
l-iditol dehydrogenase (ID)
a liver specific enzyme; serum determinations have been used in the horse to detect hepatocellular damage. Called also sorbitol dehydrogenase, SDH.
isocitrate dehydrogenase (ICD)
an enzyme found in high concentrations in many tissues. Two major forms of the enzyme, an NAD+-dependent ICD associated with the mitochondrial TCA cycle and a NADP+-dependent ICD associated with fat synthesis in adipose tissue and lactating mammary gland of ruminants or with steroidogenesis in endocrine tissues. Serum levels have been used to detect hepatocellular damage, but it is not highly specific.
lactate dehydrogenase (LDH), lactic acid dehydrogenase
an enzyme that catalyzes the interconversion of lactate and pyruvate. It is widespread in tissues and is particularly abundant in kidney, skeletal muscle, liver and myocardium. It appears in elevated concentrations when these tissues are injured. See also mouse lactic dehydrogenase elevating virus.
lactate dehydrogenase agent
polyol dehydrogenase
sorbitol dehydrogenase (SDH)
References in periodicals archive ?
NAC is a Glutathione building block that enhances alcohol metabolism by neutralizing acetaldehyde, the most common cause of negative side effects when consuming alcohol.
Biochemistry and Pathophysiology of Alcohol Metabolism After administration, alcohol (ethanol) is metabolized to acetaldehyde by the enzymatic action of alcohol dehydrogenase with NAD+ as a coenzyme.
A provider can calculate the time of alcohol metabolism by dividing the admission blood alcohol by 20 mg/dL.
91] The ALDH2*2 and ADH1B*2 alleles have cumulative dosage effects on alcoholism, and alcohol metabolism can be influenced by gender and alcohol-related-trait scores in different ways.
Additionally, both CYP1A2 and CYP3A, two other hepatocellular cytochrome P450 enzymes, coregulate alcohol metabolism that is associated with MEOS activity and lesions in hepatocytes (Hellum et al.
Since alcohol metabolism naturally occurs in the liver, it would "almost be like having millions of liver cell units inside your stomach or in your intestine, helping you to digest alcohol," he says.
Long-term booze use boosts brain levels of acetate, an energy-rich by-product of alcohol metabolism, researchers report in the April 1 Journal of Clinical Investigation.
By injecting the aforementioned inebriated mice with nanocapsules full of enzymes that are instrumental in alcohol metabolism, researchers have not only sobered the little vermin, but created a unique drug delivery technology that could disrupt the medical industry.
2005) may accelerate the weathering process by increasing the amount of time that alcohol can affect vital biophysiological processes such as the production of liver isoenzymes for alcohol metabolism, a change in the electrolyte balance in the digestive system, and longer-term exposure of the ovum to the teratogenic effects of alcohol.
This means they can't break down alcohol metabolism.
An experimental compound repaired a defective alcohol metabolism enzyme that affects an estimated 1 billion people worldwide, according to research supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA).
It is well established that accumulation of acetaldehyde, the intermediate metabolite of alcohol metabolism play a pivotal role in the development of hangover.