The differential duration of the intoxication period, excessive concentrations of alcohol at the tissue level, accelerated alcohol metabolism
and generation of ROS and alcohol metabolites, and acute disruption of antioxidant mechanisms are some of the salient differences between chronic and binge-like alcohol-mediated tissue injury.
Aizawa et al., "Aqueous components of tomato accelerate alcohol metabolism
by increasing pyruvate level," Journal of Food and Nutrition Sciences, vol.
There is no consensus in discrepancies about defining binge drinking in the scientific literature: first of all, there are different amounts of standard drink in binge drinking patterns (>5, >6, or >8) as well as different amounts of pure ethanol in a standard drink (8-20 g); second, there are differences in duration of the binge drinking sessions (from 2 to 6 hours, the whole day, or even two to four days) and drinking with or without a meal; third, there are differences in alcohol metabolism
and its distribution rate depending on sex, weight, and age .
Liver serves as the main target organ of alcohol metabolism
. Alcohol can cause several types of liver damage, including alcoholic hepatic steatosis, alcoholic hepatitis, fibrosis, and cirrhosis .
To our knowledge, it is the first time that we investigated the effects of hesperidin on regulating alcohol metabolism
, pathology, endoplasmic reticulum stress, and DNA damage in ALD on zebrafish.
Does gastric bypass alter alcohol metabolism
"When social events and gatherings call for the consumption of adult beverages, a single DEFY[R] mix before, during or after social activities can enhance alcohol metabolism
and help next-day mental alertness.
Many Japanese have a unique alcohol metabolism
compared to the Caucasian population.
Acetaldehyde, the end product of alcohol metabolism
, can prevent activation of vitamins.
It should be remembered that the pattern of alcohol drinking, at least in North American tribes, is unequal among different groups; (28) however, the presence of alcohol problem drinking in indigenous groups, as in other ethnic groups, is related to multiple factors, for indigenous may be precipitating stressors such as migration, experiences of discrimination, or economic disadvantages and even genetic variations in alcohol metabolism
. (29) For example, Yu et al (7) noted that native Americans pride in the culture and spirituality was associated significantly with fewer symptoms associated with alcohol drinking.
occurs in the liver by enzymatic action of alcohol dehydrogenase (Shepard, Tuma, & Tuma, 2010) at approximately one drink (7 g) of alcohol per hour.
In alcohol metabolism
and detoxifying metabolism liver plays the major role, liver is sensitized by induction of Cytochrome P 450 especially Cytochrome P II E for catabolism of alcohol in the process of detoxification and the metabolism of Cytochrome P 450 ROS is produced more, which are responsible for the damage of cellular proteins and membrane.