It was first described by Albers-Schonberg
, a century ago who named it "marble bone disease".
In 1907, Albers-Schonberg
described a rare developmental disorder,  in which excessive radiographic density of most or all of the bones of skeleton.
It is also known as "marble bone disease" or Albers-Schonberg disease after the German radiologist who first described the condition and radiological findings in 1904 (2-4).
Elevated serum lactate dehydrogenase isoenzymes and aspartate transaminase distinguish Albers-Schonberg disease (chloride channel 7 deficiency osteopetrosis) among the sclerosing bone disorders.
It was first described in 1904 by a German radiologist Albers-Schonberg
; hence, the disease also gets the name Albers-Schonberg
The first reference in the literature about osteopoikilosis dates from 1905, written by Stieda [9, 14]; the main characteristics were described in 1915 by Albers-Schonberg
, a German radiologist who also described osteoporosis [8, 10].
disease (autosomal dominant osteopetrosis, type II) results from mutations in the ClCN7 chloride channel gene.
Osteopetrosis was first described by a German radiologist, Albers-Schonberg
, in 1904.
It is also known as Albers-Schonberg
disease or by its Latin name, osteopathia condensans disseminata, which describes its main features.
("The Pharmaceutical Discovery Process"), B.
1] It was first reported by Albers-Schonberg
in 1904 as delayed physical development accompanied by bone fragility.
INTRODUCTION: Osteopetrosis also known as Albers-Schonberg
disease or "marble bone disease" is a descriptive term that refers to a group of rare, heritable disorders of the skeleton in which there is diffuse increase in thickness of the skeleton.