loratadine

(redirected from Alavert)
Also found in: Dictionary.
Related to Alavert: loratadine

loratadine

 [lah-rat´ah-dēn]
a nonsedating antihistamine (H1 receptor antagonist) used for treatment of allergic rhinitis and chronic idiopathic urticaria and as a treatment adjunct in asthma; administered orally.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

loratadine

Aerius (CA), Alavert, Allertin, Claritin, Claritin RediTabs, Clarityn (UK)

Pharmacologic class: Histamine1-receptor antagonist (second-generation)

Therapeutic class: Antihistamine (nonsedating)

Pregnancy risk category B

Action

Selective histamine1-receptor antagonist. Blocks peripheral effects of histamine release during allergic reactions, decreasing or preventing allergy symptoms.

Availability

Syrup: 1 mg/ml

Tablets: 10 mg

Tablets (rapidly disintegrating): 10 mg

Indications and dosages

Seasonal allergies; chronic idiopathic urticaria

Adults and children ages 6 and older: 10 mg P.O. daily

Children ages 2 to 5: 5 mg P.O. daily

Dosage adjustment

• Renal or hepatic impairment

Contraindications

• Hypersensitivity to drug

Precautions

Use cautiously in:

• renal or hepatic impairment

• elderly patients

• pregnant patients

• children younger than age 2 (safety not established).

Administration

• Give once a day on empty stomach.

• Place rapidly disintegrating tablet on tongue; give with or without water.

• Use rapidly disintegrating tablets within 6 months of opening foil pouch and immediately after opening individual tablet blister.

Adverse reactions

CNS: headache, nervousness, insomnia

EENT: conjunctivitis, earache, epistaxis, pharyngitis

GI: abdominal pain; dry mouth; diarrhea, stomatitis (in children)

Skin: rash, photosensitivity, angioedema

Other: tooth disorder (in children), fever, flulike symptoms, viral infections

Interactions

Drug-food. Any food: increased drug absorption

Patient monitoring

• Watch for adverse reactions, especially in children.

• Assess patient's response to drug.

• Watch for new symptoms or exacerbation of existing symptoms.

Patient teaching

• Advise patient to take exactly as prescribed, once a day on empty stomach.

• Tell patient to report persistent or worsening symptoms.

• Instruct patient to report adverse reactions, such as headache or nervousness.

• Caution patient to avoid driving and other hazardous activities until he knows how drug affects concentration and alertness.

• As appropriate, review all other significant adverse reactions and interactions, especially those related to the foods mentioned above.

McGraw-Hill Nurse's Drug Handbook, 7th Ed. Copyright © 2013 by The McGraw-Hill Companies, Inc. All rights reserved

loratadine

(lôr-ăt′ə-dēn′)
n.
A nonsedating antihistamine, C22H23ClN2O2, used to treat allergic rhinitis and other allergic disorders.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

loratadine

An ANTIHISTAMINE drug used to treat hay fever and other allergic disorders.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

antihistamine 

Any substance that reduces the effect of histamine or blocks histamine receptors, usually the histamine 1 (H1) receptor. It is used in the treatment of allergic conjunctivitis and also in the temporary relief of minor allergic symptoms of the eye. Common agents include antazoline sulfate, azelastine hydrochloride, cetirizine, chlorphenamine, emedastine, epinastine hydrochloride, ketotifen, levocabastine, loratadine and olopatadine. See hypersensitivity; mast cell stabilizers.
Millodot: Dictionary of Optometry and Visual Science, 7th edition. © 2009 Butterworth-Heinemann
References in periodicals archive ?
* Comment: Alavert's active ingredient is the nonsedating antihistamine loratadine, initially approved as the prescription drug Claritin.
As retailers nationwide were preparing for the launch of the OTC nonsedating antihistamines (NSAs) Claritin and Alavert in 2002, there were many questions regarding the incremental revenue these new products would bring, what impact they would have on the leading brands, and how much space should be allocated to them.
Medicate: You can get various antihistamines over the counter; Claritin and its generic equivalent, Alavert, are effective for many allergy sufferers.
Today Claritan competes with Warner-Lambert Co.'s Benedryl and Wyeth's Alavert.
Schering-Plough Corp.'s Claritin, for example, had more equity at the time it went O-T-C than Wyeth's Alavert or private label loratadine products because of its prescription heritage, explains Doyle.
year ago share (millions) BRAND PRIVATE LABEL $402.9 26.4% 23.2% 87.2 CLARITIN 130.0 20.2 7.5 11.6 CLARITIN D 117.8 106.6 6.8 10.3 BENADRYL 115.9 -4.2 6.7 20.5 ALAVERT 59.0 98.2 3.4 5.0 THERAFLU 57.7 5.9 3.3 11.1 TYLENOL SINUS 55.6 6.0 3.2 10.0 TYLENOL COLD 55.2 -10.1 3.2 10.2 ALKA SELTZER PLUS 54.6 -11.0 3.1 10.5 SUDAFED 54.3 -0.8 3.1 9.3 VENDOR PRIVATE LABEL $402.9 26.4% 23.2% 87.2 SCHERING-PLOUGH 346.0 35.4 19.9 34.4 PFIZER 295.7 -1.4 17.0 52.3 MCNEIL CONSUMER PRODS.
Among the top-selling products are Claritin, supplied by Schering-Plough HealthCare Products Inc.; Benedryl, manufactured by Warner-Lambert Co.; and Alavert, supplied by Wyeth.
From Claritin and Alavert to Prilosec OTC to new forms of smoking-cessation products, the past two years have seen a number of prominent switches that bring a wider array of options to consumers.
Dollar sales in the category advanced 14.2%, with consumer interest driven by the extensive advertising campaigns for such products as Schering-Plough HealthCare Products Inc.'s Claritin and Johnson & Johnson Co.'s Alavert.
Wyeth Consumer Healthcare's Alavert, another product switched from prescription to over-the-counter status, dropped three places to seventh.
Moreover, sales of Claritin, Claritin D and Alavert, another branded version of Loratadene from Wyeth, accounted for no less than $335 million in sales during the 52 weeks ended January 25--nearly 19% of the segment's total sales of $1.77 billion.