Alatrofloxacin | definition of alatrofloxacin by Medical dictionary
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a broad-spectrum antibacterial
that is the prodrug
, to which it is rapidly converted after intravenous infusion; used in the form of the mesylate salt.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
References in periodicals archive
anthracis Sterne) to 21 sequential subcultures in subinhibitory concentrations of doxycycline, ciprofloxacin, alatrofloxacin
, and gatifloxacin.
anthracis longer than were ciprofloxacin or alatrofloxacin
, while clarithromycin was effective longer than either erythromycin or azithromycin.
The FDA issued a public health advisory in June on trovafloxacin (the oral formulation marketed as Trovan) and alatrofloxacin
(the intravenous formulation marketed as Trovan-IV).
The restrictions apply to both the oral (trovafloxacin) and IV (alatrofloxacin
) formulations of the quinolone anti- biotic, which has been prescribed 2.5 million times since Pfizer launched it in February 1998.