Alabama rot was first discovered in the US state in the 1980s and killed greyhounds - before fizzling out.
These symptoms don't just arise from Alabama rot so dog owners need to be vigilant and get their pets checked out if they spot them.
The mysterious illness, called Alabama rot and which cannot be prevented, affects all breeds of dog and has seen at least 46 cases confirmed in England and Wales since December 2013.
Huw Stacey, head of clinical services at Vets4Pets, which has issued an interactive guide for animal owners, said: "The concern among vets in the UK is that, unlike the Alabama rot that affected greyhounds in America, the disease does not seem to target any specific breed, age, sex or weight of dog.
Possible cases of Alabama rot, which causes skin lesions and kidney failure, were identified in 71 dogs across the UK between November 2012 and March 2014.
Researchers identified 30 possible cases of Alabama rot, including in five English springer spaniels, four flat-coated retrievers and two border collies.
The key message is that this condition has affected a very small number of dogs and that most skin lesions will not be related to this disease, and most cases of kidney injury in dogs will not turn out to be from Alabama Rot.
Mr McVey added: "The actual cause of Alabama Rot is unknown.
It also flagged up a concern about the spread of Alabama rot
around Greater Manchester and the New Forest.
was first reported in greyhounds in America in the 1980s.
The condition appears similar to Alabama rot
, seen in the 1980s in US greyhounds, although the UK version appears to have some basic differences.
Apparently the first case was more than 12 months ago and, rather worryingly, vets are still not sure what is causing the condition, which is being likened to Alabama Rot
, a disease that affected dogs in the States in the 1980s.