Akabane virus

Ak·a·bane vi·rus

(ă-kă-bă-nā),
a virus of the genus Bunyavirus, family Bunyaviridae, causing abortion in cattle and congenital arthrogryposis and hydranencephaly in bovine fetuses in Israel, Japan, and Australia; it is transmitted by mosquitoes.
Farlex Partner Medical Dictionary © Farlex 2012

Akabane virus

An arbovirus first identified in the Akabane district in Japan, which passes through the placenta of early embryos in cattle and causes congenital neurologic problems in calves.

Vector
Haematophagous midges (Culicoides brevitarsus).
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
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Among the EHDV rRT-PCR-positive samples, 18 were also rRT-PCR-positive for BTV and 1 was positive in pan-Simbu rRT-PCR (7), showing Akabane virus infection.
Other viruses, such as Akabane virus, Rift Valley Fever virus, Cache Valley virus, Border disease virus, and Wesselsbron disease virus, are also associated with the occurrence of CNS malformations (OBERST, 1993), but these viruses have not yet been diagnosed in cattle in Brazil.
Congenital abnormalities in newborn lambs after infection of pregnant sheep with Akabane virus. Infect Immun.
Estao incluidos patogenos virais de significante importancia humana e veterinaria, tais como, Crimean-Congo hemorrhagic fever virus (CCHFV), Rift Valley fever virus (RVFV), Akabane virus (AKAV), Nairobi sheep disease virus (NSDV), Aino virus (AINV) e Peaton virus (PEAV) (4), assim como virus ja isolados na Amazonia Brasileira como: Guaroa virus (GROV), Maguari virus (MAGV), Tacaiuma virus (TCMV), Guama virus (GMAV), Caraparu virus (CARV), Oropouche virus (OROV), Catu virus (CATUV), Icoaraci virus (ICOV) e Belem virus (BLMV), entre outros (2).
Several of these viruses, such as Akabane virus, Aino virus, and Schmallenberg virus, are arboviruses associated with abortion, premature birth, stillbirth, and congenital malformations in ruminants (2-4).
Akabane virus (AKAV), Aino virus (AINV), and Schmallenberg virus are the most studied in this serogroup; Shuni, Sabo, Shamonda, and Sango viruses (1,2) are examined less frequently.
Genetic diversity and reassortments among Akabane virus field isolates.
Similar to the situation with Akabane virus infection (8), the clinical picture shown by in utero SBV-infected newborn calves is likely to depend largely on the age of the fetus at the time of infection.
Tsutsui and colleagues (9) showed that dairy calves lost their maternally derived antibodies against Akabane virus at -4 months of age, and Grimstad and colleagues (10) showed that young white-tailed deer lost their maternally derived antibodies against Jamestown Canyon virus at 5-6 months of age.
In contrast, viremia was detected in most cows that were artificially inseminated and simultaneously inoculated in the uterus with cell culture--passaged Akabane virus, a teratogenic orthobunyavirus closely related to SBV (9).
The Simbu serogroup (family Bunyaviridae, genus Bunyavirus) includes Shamonda virus, Akabane virus, Sathuperi virus, and Aino virus.
Similar to Akabane virus (AKAV), another Simbu serogroup virus, SBV can cause fatal congenital defects by infection of fetuses during a susceptible stage in pregnancy (2).