NLRP3

(redirected from Aii)
Also found in: Acronyms.

NLRP3

A gene located on chromosome 1q44 that encodes a pyrin-like protein that interacts with the apoptosis-associated speck-like protein PYCARD/ASC. NLRP3 has a caspase recruitment domain, and belongs to the NALP3 inflammasome complex; it plays a role in regulating inflammation and apoptosis.
 
Molecular pathology
NLRP3 mutations are associated with chronic infantile neurological cutaneous and articular (CINCA) syndrome, familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome and neonatal-onset multisystem inflammatory disease (NOMID).
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
The Aii covers nearly 200 firms from more than 20 industries, based on experiences captured from a nationally representative online survey of over 7,000 U.S.
Animals were divided into 12 experimental groups (6 for AII and 6 for Adr): Control (absence of antagonists), Los, Pro, Pra, Los + Pro, and Pro + Pra.
The MulteFire Alliance and AII will collaborate on the following:
Aii has celebrated the 45th anniversary of the Ardell brand with various events and promotions designed to thank its partners for their continued support of both the brand and the entire lash category.
The contracts allegedly were favorable to AII because it allowed Cojuangco's firm to increase the price of the coconut seed nuts.
This study revealed the novel finding that the vasoconstrictor responses elicited by AII but not AVP or 5-HT were markedly reduced in OAs from 2K-1C rats.
As it is evident from Figure 1, on the background of mild downward trend in the incidence of AII in Mangistau, there are significant fluctuations in performance from year to year.
Oil drop (430 mg: AII) formed in the concentrate was separated from solid compounds and used for further study.
'Industrialists have the initiative to choose their project and consortium,' explained the spokesperson from AII, indicating that Quaero had not yet completed all stages.
Figure 1 Differences in Income and Education Among Elderly Medicare+Choice (M+C) Enrollees with IHD or CHF Compared to AII M+C Enrollees: 1998 All Male Female Annual Household Income Less Than $10,000 AII 15 9 20 IHD 17 9 26 CHF 22 13 30 Less Than 12 Years of Education AII 31 30 32 IHD 35 32 39 CHF 42 39 44 NOTE: IHD is ischemic heart disease; CHF is congestive heart failure.