NLRP3

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NLRP3

A gene located on chromosome 1q44 that encodes a pyrin-like protein that interacts with the apoptosis-associated speck-like protein PYCARD/ASC. NLRP3 has a caspase recruitment domain, and belongs to the NALP3 inflammasome complex; it plays a role in regulating inflammation and apoptosis.
 
Molecular pathology
NLRP3 mutations are associated with chronic infantile neurological cutaneous and articular (CINCA) syndrome, familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome and neonatal-onset multisystem inflammatory disease (NOMID).
References in periodicals archive ?
Enhancing brands while paying tribute to their heritage is a balancing act, particularly as Aii has been very active in the past several decades with acquisitions.
The contracts allegedly were favorable to AII because it allowed Cojuangco's firm to increase the price of the coconut seed nuts.
At the same time, the average annual incidence of AII in Aktau (138.
Earlier reports indicated that the AI sub-assemblage and the B assemblage, regardless of the B sub-assemblages, have a broad host range, including pets, wildlife, and livestock while the AII sub-assemblage is more limited to human subjects (2,33).
As shown Figure 3, nuclear extracts from PMA-stimulated EL4 T cells (treated with AII fraction) and nuclear extract from nonstimulited EL4 T cells (treated with Sill fraction) exhibited strong NF-AT-binding activity in the electrophoretic mobility shift assays using a labeled oligonucleotide containing a consensus NF-AT site.
Figure 2 Differences in the Percent of Elderly Medicare+Choice (M+C) with IHD and CHF Who Report Three or More Chronic Conditions Compared to All M+C Enrollees: 1998 All Male Female AII 47 45 48 IHD 86 82 90 CHF 92 92 93 NOTE: IHD is ischemic heart disease; CHF is congestive heart failure.
An unnamed [Tera] product will be available at Nexpo, and we intend to take that on, too," said former Atex sales chief Barry Truitt, who most recently was with net-linx before joining AII as its front-end systems business director.
The AII initiative was proposed by Goh at the ASEAN summit in Hanoi in December last year.
The AII corporate IS mandate for common systems just reinforced the image of the corporate IS group as being out of touch with the business.
Market Vectors Australia will market and distribute exchange-traded funds (ETFs), including six existing Aii ETFs, to the Australian marketplace.
Bombardier Aerospace yesterday (10 May 2010) confirmed that the order for five NextGen aircraft, announced on 3 August 2009, was placed by AII Nippon Airways Co Ltd, of Tokyo Japan.
The multimedia applications were provided by Nokia's experimental AII IP Mobility Core system and application servers.