AIDS dementia complex

(redirected from Aids dementia)

AIDS de·men·ti·a com·plex (ADC),

a subacute or chronic HIV-1 encephalitis, the most common neurologic complication in the later stages of HIV infection; manifested clinically as a progressive dementia, accompanied by motor abnormalities.
Farlex Partner Medical Dictionary © Farlex 2012

AIDS Dementia Complex

An insidious metabolic encephalopathy affecting up to two-thirds of AIDS patients, which is triggered by HIV and driven by neurotoxins secreted by macrophages and microglia. It may be complicated by infections—e.g., Toxoplasma gondii, CMV, or lymphomas.
Clinical findings Poor concentration, loss of memory, incoordination, dysgraphia, lethargy, apathy.
Note: 30% of asymptomatic HIV-positive subjects have EEG abnormalities or progressive cognitive, motor, or behavioural dysfunction.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

AIDS dementia complex

AIDS An insidious–30% of asymptomatic HIV-positive subjects have EEG abnormalities, progressive cognitive, motor, behavioral dysfunction, which affects up to 2⁄3 of AIDS Pts; ADC may be complicated by infections–eg, Toxoplasma gondii, CMV, lymphomas Clinical Inability to concentrate, loss of memory, gait incoordination, dysgraphia, slowing of psychomotor functions and eventually, apathy Pathology Degeneration of subcortical white matter and deep gray matter, white matter vacuolization in the lateral and posterior columns of the spinal cord
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

AIDS dementia complex

A feature of certain cases of AIDS in which there is so much direct damage to brain cells by HIV that DEMENTIA occurs. The condition occurs in some 20% of people with untreated AIDS in the late stages. The drug ZIDOVUDINE appears to be capable of greatly reducing the likelihood of this effect. Other anti-AIDS drugs may be less useful in preventing ADC.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

AIDS dementia complex

A type of brain dysfunction caused by HIV infection that causes difficulty thinking, confusion, and loss of muscular coordination.
Mentioned in: AIDS
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.

AIDS de·men·ti·a com·plex

(ADC) (ādz dĕ-menshē-ă kompleks)
Subacute or chronic HIV-1 encephalitis, the most common neurologic complication in the later stages of HIV infection.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
Evidence for a change in aids dementia complex in the era of highly active antiretroviral therapy and the possibility of new forms of aids dementia complex.
A love of football aids dementia victims A love of football aids dementia victims THE Football Memories project is helping men with dementia by reviving memories of players, matches, goals and incidents from football matches in their younger days.
The researchers analysed samples of blood and cerebrospinal fluid from HIV-infected subjects who were taking efavirenz in the North Eastern AIDS Dementia study.
For the study led by Haughey, researchers obtained samples of blood and cerebrospinal fluid from HIV-infected subjects enrolled in the NorthEastern AIDS Dementia study who were taking efavirenz.
RNA viroid induced mRNA interference can contribute to cell death in AIDS dementia, malignant transformation and autoimmunity in the acquired immunodeficiency syndrome.
Timed gait test: normative data for the assessment of the AIDS dementia complex.
* Rehabilitation (physical, psychosocial and spiritual) for patients presenting with advanced AIDS, including AIDS dementia)
Factors in AIDS dementia complex trial design: results and lessons from the abacavir trial.
Most entries have been revised, including those on autism spectrum disorders, atherosclerosis, learning disabilities, neurofibromatosis, polio, rabies, antidepressants, aphasia, AIDS dementia complex, Alzheimer's disease, ADHD, and chronic fatigue and immune dysfunction syndrome.
The HIV-positive subjects were classified into three groups: 124 were neurologically asymptomatic, 66 had AIDS dementia complex (ADC) stage 0.5, and 50 had ADC stage 1-3.

Full browser ?