AIDS dementia complex(redirected from Aids dementia)
AIDS de·men·ti·a com·plex (ADC),
a subacute or chronic HIV-1 encephalitis, the most common neurologic complication in the later stages of HIV infection; manifested clinically as a progressive dementia, accompanied by motor abnormalities.
Farlex Partner Medical Dictionary © Farlex 2012
AIDS Dementia ComplexAn insidious metabolic encephalopathy affecting up to two-thirds of AIDS patients, which is triggered by HIV and driven by neurotoxins secreted by macrophages and microglia. It may be complicated by infections—e.g., Toxoplasma gondii, CMV, or lymphomas.
Clinical findings Poor concentration, loss of memory, incoordination, dysgraphia, lethargy, apathy.
Note: 30% of asymptomatic HIV-positive subjects have EEG abnormalities or progressive cognitive, motor, or behavioural dysfunction.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
AIDS dementia complexAIDS An insidious–30% of asymptomatic HIV-positive subjects have EEG abnormalities, progressive cognitive, motor, behavioral dysfunction, which affects up to 2⁄3 of AIDS Pts; ADC may be complicated by infections–eg, Toxoplasma gondii, CMV, lymphomas Clinical Inability to concentrate, loss of memory, gait incoordination, dysgraphia, slowing of psychomotor functions and eventually, apathy Pathology Degeneration of subcortical white matter and deep gray matter, white matter vacuolization in the lateral and posterior columns of the spinal cord
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
AIDS dementia complexA feature of certain cases of AIDS in which there is so much direct damage to brain cells by HIV that DEMENTIA occurs. The condition occurs in some 20% of people with untreated AIDS in the late stages. The drug ZIDOVUDINE appears to be capable of greatly reducing the likelihood of this effect. Other anti-AIDS drugs may be less useful in preventing ADC.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
AIDS dementia complex
A type of brain dysfunction caused by HIV infection that causes difficulty thinking, confusion, and loss of muscular coordination.
Mentioned in: AIDS
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
AIDS de·men·ti·a com·plex(ADC) (ādz dĕ-menshē-ă kompleks)
Subacute or chronic HIV-1 encephalitis, the most common neurologic complication in the later stages of HIV infection.
Medical Dictionary for the Dental Professions © Farlex 2012