agrin


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Agrin

A 150-kD extracellular matrix proteoglycan encoded by AGRN on chromosome 1p36.33, which plays a central role in the embryonic development of the neuromuscular junction, first identified in the synapse-rich electric organ of Torpedo californica which induces myotubular synaptic specialisation.

agrin

A protein released by motor neurons that brings about the close aggregation of acetylcholine receptors on muscle cells.
References in periodicals archive ?
5302G>C) in exon 31 of AGRN leading to the substitution of alanine to proline in the C-terminal LG2 domain of agrin (p.
14) No entanto, alem do vinagre de vinho, existem outros que tambem sao utilizados, entre estes estao, os vinagres de maca, de arroz, agrin tinto, agrin branco, de laranja.
As a first step in laying down the junction, motor neurons release the protein agrin, which reaches out to LRP4, a protein on the muscle cell surface.
The three leading characters of Turtles Can Fly are in their early teens: a smart operator nicknamed Satellite; a youth called Henkov, who lost both his arms in a mine explosion; and Henkov's sister, Agrin, gentle but desperately resigned to the grayness of her existence.
To analyze nestin, the group employed mice in which the positive, synapse-stabilizing factor known as agrin had been genetically eliminated.
Candidate polysaccharide or proteoglycan subunits include aggrecan, agrin, bamacan, heparan sulfate, chondroitin sulfate, keratan sulfate, versican, phosphocan, perlecan, hyaluronan, decorin, dermatan sulfate, biglycan, fibromodulin, alginate, polylactate, polyglycolic acid, starch, dextran, agarose, chitan, chitosan, and heparin.
Applications: Anti-wrinkle formulations Comments: Inyline is a hexapeptide that targets the agrin/MuSK post-synaptic pathway acting as a competitive antagonist of MuSK (Muscle-Specific Kinase) at the agrin binding site.
Alfa distroglikanin azalmis glikozilasyonu, kasta merozin, agrin ve perlekan, beyinde de noroksin gibi baglarin bazal membrana iyi yapisamamasina yol acaktadir.
15 PRELP CAG47066 XM_001630052 2e-15 Other extracellular matrix proteins Agrin CAI15575 XM_001632399 3e-75 Asporin CAI16697 XM_001638871.
As substancias atrativas avaliadas foram: suco de uva comercial, marca Maguari, diluido a 25%; hidrolisado enzimatico de proteina, subproduto da refinaria de milho, marca Bio Anastrepha (5%), contendo borax (pH entre 8,5 e 9,0), e vinagre fermentado acetico de alcool e vinho, da marca Chemim Agrin, diluido a 25%.