Therefore, the ethyl acetate extraction proved to be an efficient technique to extract compounds that confer antioxidant properties to Agrimonia eupatoria infusion.
This antioxidant activity could be responsible for the anti-inflammatory properties of Agrimonia eupatoria. Superoxide anion is an inflammatory mediator and it reacts with NO originating peroxynitrite, which is a powerful oxidant that is also involved in the inflammatory processes.
Antioxidant, anti-inflammatory, and peripheral analgesic activities were observed for both the Agrimonia eupatoria infusion and/or its polyphenol-enriched fraction at nontoxic doses for the liver and the kidneys.
The results of the present work corroborate the traditional use of the Agrimonia eupatoria infusion as antioxidant and anti-inflammatory and suggests that its polyphenols contribute to this activity, which may be helpful in developing novel and beneficial antioxidants, anti-inflammatory, and/or peripheral analgesic agents.
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