Agranulosis


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.
Related to Agranulosis: agranulocytosis

Agranulocytosis

A marked decrease in neutrophils < 500/mm3; it is loosely equivalent to neutropaenia in the working parlance.
Artiology Acquired due to prescription drugs—chloramphenicol, clozapine, nitrous oxide, procainamide, sulfonamides, thiazide diuretics.
Clinical findings Fever, malaise, mucocutaneous ulcers (throat, GI tract, skin).