Aggressive Digital Papillary Adenocarcinoma

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Aggressive Digital Papillary Adenocarcinoma

A rare, often painful variant of sweat gland carcinoma that occurs on the palmo-plantar surfaces of the hand and foot and which may become clinically aggressive. It is more common in men, has a mean age at presentation of 52, averages 1.7 cm in greatest dimension and may be present for up to 15 years. The term "aggressive digital papillary adenoma" has been abandoned, given that despite their bland appearance, they often behave aggressively.
Prognosis Up to 14% metastasise; 40–50% recur locally.
Management Aggressive surgical re-resection or amputation if necessary to avoid local recurrence.
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References in periodicals archive ?
Aggressive digital papillary carcinoma (aggressive digital papillary adenoma and adenocarcinoma revisited).
The entity "aggressive digital papillary adenoma" was initially described in 1979 by Helwig at the Armed Force Institute of Pathology (AFIP) who later differentiated between "aggressive digital papillary adenoma" and "aggressive digital papillary adenocarcinoma" in a 1987 case series [1,3].
Helwig, "Aggressive digital papillary adenoma," in Proceedings of the American Academy of Dermatology Clinical Pathology Conference, Chicago, Ill, USA, December 1979.

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