AFP

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alpha

 [al´fah]
the first letter of the Greek alphabet, α; used to denote the first position in a classification system; as, in names of chemical compounds, to distinguish the first in a series of isomers, or to indicate the position of substituent atoms or groups; also used to distinguish types of radioactive decay, brain waves or rhythms, adrenergic receptors, and secretory cells that stain with acid dyes, such as the alpha cells of the pancreas.
alpha-adrenergic blocking agent (alpha-blocker) (alpha-blocking agent) any of a group of drugs that selectively inhibit the activity of alpha receptors in the sympathetic nervous system. As with beta-adrenergic blocking agents, alpha-blocking agents compete with the catecholamines at peripheral autonomic receptor sites. This group includes ergot and its derivatives, and phentolamine.
alpha chain disease the most common heavy chain disease, occurring predominantly in young adults in the Mediterranean area, and characterized by plasma cell infiltration of the lamina propria of the small intestine resulting in malabsorption with diarrhea, abdominal pain, and weight loss, or, exceedingly rarely, by pulmonary involvement. The gastrointestinal form is immunoproliferative small intestine disease.
alpha-fetoprotein (AFP) a plasma protein produced by the fetal liver, yolk sac, and gastrointestinal tract and also by hepatocellular carcinoma, germ cell neoplasms, and other cancers in adults; elevated levels may also be seen in benign liver disease such as cirrhosis and viral hepatitis. The serum AFP level is used to monitor the effectiveness of cancer treatment.

During pregnancy some AFP crosses from the amniotic fluid to the mother's blood. If the fetus has a neural tube defect, large amounts of AFP will be found in the amniotic fluid and maternal blood. Blood screening tests for serum AFP can thus be done as a first step in the screening process; if test results are positive, further testing is indicated to diagnose the defect.
alpha particles a type of emission produced by the disintegration of a radioactive substance. The atoms of radioactive elements such as uranium and radium are very unstable, continuously breaking apart with explosive violence and emitting particulate and nonparticulate types of radiation. The alpha particles, consisting of two protons and two neutrons, have an electrical charge and form streams of tremendous energy when they are released from the disintegrating atoms. These streams of energy (alpha rays) can be used in treatment of various malignancies. See also radiation and radiation therapy.

AFP

Abbreviation for α-fetoproteins. See: fetoproteins.

AFP

abbr.
alpha-fetoprotein

AFP

A gene on chromosome 4q11-q13 that encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during foetal life. AFP is regarded as the foetal counterpart of serum albumin and binds copper, nickel, fatty acids and bilirubin; hereditary persistance of alpha-fetoprotein may be found in individuals with no obvious pathology.

Molecular pathology
AFP is elevated in foetuses with neural tube defects, including spina bifida and anencephaly. It is elevated in adults with hepatocellular carcinomas and germ cell tumours.

AFP

α-fetoprotein, see there.

AFP

Abbreviation for alpha(α) fetoprotein test.

AFP (Alpha-fetoprotein)

A tumor marker associated with liver, testicular, and ovarian cancer.
Mentioned in: Tumor Markers
References in periodicals archive ?
Agence France-Presse (AFP) recently reported that the Michelin group and the Paul Scherrer Institute (PSI) introduced during the Challenge Bibendum competition in Shanghai, China earlier this month a prototype electric car powered by an oxygen and hydrogen fuel cell.
The ban led to outbreaks of polio in nine African countries previously declared polio-free, according to an Agence France-Presse report.
"It was never our intention to offend people's beliefs," company spokesman Jens Nielsen told Agence France-Presse. Local Catholic parishes charged blasphemy.
"With this report," commented Bessy in a rare response to the media, a declaration to the French wire service, Agence France-Presse, "they are hoping to destroy a school that is internationally recognized.
Reuters, Agence France-Presse in International Herald Tribune, Nay 25 & Environmental News Service, May 27
Lee told Agence France-Presse the company has achieved 53 per cent of its $999.2 billion South Korean annual cost-cut target in the first two months of 2001.
Said delegate Chia Slow Yue of the Institute of Southeast Asian Studies in a 19 June 2000 Agence France-Presse article, "If Asia's environment is to survive the next century without completely collapsing, governments in the region must make environmental issues equal in priority to economic development."
Agence France-Presse reports that the future European aerospace giant EADS and US-based Northrop Grumman announced during the Berlin airshow that they have signed a letter of intent to form a new alliance in defense electronics and radar.
The Agence France-Presse earlier reported in a dispatch from Detroit that Ford is trying to convince Honda to sell itself.
" According to Agence France-Presse, the 21-year-old suspect Kazuhiro Kusakabe drove a small vehicle into Takeshita Street in Tokyo's fashion district of Harajuku at 10 minutes past midnight with an "intent to murder." Local media reports said the suspect told police he was acting in "retribution for the death penalty" without elaborating on what he meant.
by Agence France-Presse AC Milan have sacked coach Vincenzo Montella.
President of the Palestinian Prisoner Society Qadourah Faris told Agence France-Presse (AFP) that the prisoners suspended their hunger strike after concluding an agreement with Israel, allowing prisoners to receive two visitors per month.

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