African trypanosome


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African trypanosome

n.
Any of various trypanosomes of sub-Saharan Africa that are transmitted by tsetse flies and cause sleeping sickness in humans and nagana in livestock.
References in periodicals archive ?
African trypanosome antigens recognized during the course of infection in N'Dama and Zebu cattle.
Obado et al., "High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome," Genome Research, vol.
Mitochondrial transcript maturation in African trypanosomes and other kinetoplastid organisms requires RNA editing in order to generate functional mRNAs.
Hybrid formation between African trypanosomes during cyclical transmission.
Thus, this is a plausible approach for developing new drugs and/or vaccines targeting [[Ca.sup.2+.+]] homeostasis in African trypanosomes. This study was supported by the Minority Biomedical Research Support Program, NIH-NIGM-MBRS/RISE (GM58268), at Morehouse School of Medicine and the National Institutes of Health, NIH-RCMI (RR033062).
Use of identical images to illustrate East African and West African trypanosomes is unacceptable.
African trypanosomes are highly reliant on antigenic variation for their longterm survival - the process is so successful that trypanosomes can infect their host for many months and in some cases years.
vivax is substantially different than that of T brucei and very likely different from those of other African trypanosomes [9].
The chemotherapy of African trypanosomes is beset with several problems; these include limited repertoire of trypanocides, resistance to drugs, and toxicity to a protracted treatment protocol [5-7].
Release of the variant surface antigens of African trypanosomes, agents of a reemerging infectious disease in sub-Saharan Africa, occurs not only by proteolysis but also by glycosylphosphatidylinositol-anchor hydrolysis through a phospholipase present in the parasite surface.

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