africae and confirmed the diagnosis of African tick-bite fever
African tick-bite fever
(ATBF), a recently rediscovered rickettsiosis of the spotted fever group, is caused by Rickettsia africae, an obligate intracellular, gram-negative, rod-shaped bacterium, transmitted by cattle ticks of the Amblyomma genus (1-5).
Rickettsia africae is a recently described spotted fever group (SFG) rickettsia that is the agent of African tick-bite fever
(ATBF), a mild but common tickborne disease of local persons and tourists, in particular, in sub-Saharan Africa.
The estimated incidence of African tick-bite fever
in safari travelers is 4%-5.
To date, African tick-bite fever
has been characterized as a mild illness.
africae, has been identified as the agent of African tick-bite fever
africae, which cause Mediterranean spotted fever (MSF) and African tick-bite fever
(ATBF), respectively, have been associated with human disease in the region; ATBF is more frequently associated with travel (1).
In contrast, African tick-bite fever
, a rickettsiosis due to R.
Though neither cardiac symptoms nor a rash developed, the latter is sometimes lacking in other spotted fever group rickettsioses, such as African tick-bite fever