Bantu siderosis

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Bantu siderosis

Excessive iron stores in the body due to a large intake of beer prepared in iron pots. The condition can lead to CIRRHOSIS of the liver.
References in periodicals archive ?
African iron overload. Semin Haematol 2002;39:263-269.
Hereditary hemochromatosis must be distinguished from other conditions that cause iron overload, such as porphyria cutanea tarda, [beta]-thalassemia, medicinal and transfusional iron overload, and African iron overload (46).
In African iron overload, heterozygous TF CD individuals might be partly protected from increased iron accumulation.
Is there a link between African iron overload and the described mutations of the hereditary haemochromatosis gene?
The subjects were 178 volunteers from rural Swaziland and rural Zimbabwe, who were studied from 1993 to 1995 as part of an investigation of families with African iron overload and of community members with a history of traditional beer consumption.
In the present study, we provide evidence that circulating transferrin receptor concentrations are inversely and significantly proportional to indirect measures of the size of the body's iron stores, and that receptor concentrations are significantly less in subjects with African iron overload than in normal and iron-deficient subjects.
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