Afipia

Afipia

(ă-fip'ē-ă),
A genus of gram-negative, oxidase-positive, motile, nonfermenting bacteria that have been placed in the class Proteobacteria. They are morphologically variable, appearing as rods or filaments that may stain poorly. More than 10 species have been identified; originally reported to be the agent of catscratch disease, their current pathogenic role remains uncertain. The type strain is A. felis. Other human isolates are A. clavelandensis and A. broomeae.

A·fip·i·a

(ă-fip'ē-ă)
A genus of gram-negative, oxidase-positive, motile, nonfermenting bacteria that have been placed in the class Proteobacteria. They are morphologically variable, appearing as rods or filaments that may stain poorly. More than 10 species have been identified, one of which was formerly thought to be the cause of catscratch disease. Their current pathogenic role is uncertain. The type strain is A. felis.
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The most well-known of these are Bartonella species (henselae, quintana, bacilliformis), although some Afipia species (eg, A.
By 1992 the name Afipia felis was proclaimed to be the agent causing CSD (Afipia is an acronym for the Armed Forces Institute of Pathology and felis refers to the vector of this infection).
Serologic response to Bartonella and Afipia antigens in patients with cat scratch disease.
In the case of cat-scratch disease, the exact cause - a bacterium called Afipia felis - was not discovered until 1983, although the disease had been recognized for nearly 100 years.
Isolation of new fastidious alpha Proteobacteria and Afipia felis from hospital water supplies by direct plating and amoebal co-culture procedures.
Bartonella and Afipia species emphasizing Bartonella henselae.
micdadei, and other AAMs (15,18), including Parachlamydia acanthamoeba (strain BN 9 and "Hall's coccus"), Afipia birgiae, A.
Etiology of cat scratch disease: comparison of polymerase chain reaction detection of Bartonella (formerly Rochalimaea) and Afipia felis DNA with serology and skin tests.
thiooxydans, Mesorhizobium amorphae, Azorhizobium caulinodans, Afipia jelis, A.
In addition, use of amoebal coculture procedures (10) allows recovery of some fastidious gram-negative bacteria, such as the Legionella-like amoebal pathogens (11,12), Candidatus Odyssella thessalonicensis (13), Sacrob ium lyticum (14), several Afipia species (15), and Chlamydia-like endosymbionts (16,17).
Conversely, in the absence of serologic evidence, the role of a cultured organism should be interpreted cautiously, as shown by the example of Afipia fells, which was first thought to be the cause of cat-scratch disease, but was finally identified as a water contaminant (12,43).
We tested serum specimens from three groups of patients with pneumonia by indirect immunofluorescence against Legionella-like amoebal pathogens (LLAPs) 1-7, 9, 10, 12, 13; Parachlamydia acanthamoeba strains BN 9 and Hall's coccus; and Afipia felis.