For each person, the researchers determined the fraction of sugar committed to aerobic glycolysis
in various regions of the brain.
LPS-activated dendritic cells and M1-like activated macrophages show enhanced aerobic glycolysis
, flux through the pentose phosphate pathway, and fatty acid synthesis but have incomplete OXPHOS at the level of succinate dehydrogenase (SDH) and isocitrate dehydrogenase, blocking the synthesis of mitochondrial ATP.
Phosphoproteomic results are in agreement with the prevalence of aerobic glycolysis
in lines #61 and #74 of cluster 2.
Caption: Figure 1: A model of interactions between the canonical Wnt/beta- catenin pathway and PPAR gamma under aerobic glycolysis
conditions in colon cancer.
 suggest that cancer cells stimulate aerobic glycolysis
in the human brain is associated with development and neotenous gene expression.
This type of molecule might have the potential to inhibit or reverse aerobic glycolysis
in cancer, an intriguing, but still unproven, approach to cancer chemotherapy.
Increased levels of HIF-1 resulting in upregulation of its target proteins equip clear-cell RCC cells with a specific set of enzymatic machinery that favours aerobic glycolysis
over oxidative phosphorylation.[sup.8] One of the genes controlled by HIF-1 (because it contains an HRE site) is glucose transporter 1 (Glut1), which encodes a membrane transporter of glucose.
A high aerobic capacity is beneficial to a performer in an anaerobic event as it will aid a faster recovery between bouts of high-intensity exercise and provide a greater amount of ATP via aerobic glycolysis
Catabolic efficiency of aerobic glycolysis
: the Warburg effect revisited.
Many cancers seem to employ aerobic glycolysis
as their metabolic programme of choice to fulfil their bioenergetic and anabolic requirements for rapid growth and enhance their survival in response to microenvironmental stress [11-15].
From there, glucose 6-phosphate can be used as a substrate by aerobic glycolysis
or by the pentose-phosphate pathway (PPP).