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APICAcenocoumarol vs Pentoxifylline in Intermittent Claudication. A trial studying the safety and efficacy of pentoxifylline and/or acenocoumarol in treating intermittent claudication associated with chronic occlusive arterial disease.
Conclusion Pentoxifylline is safe and effective for treating intermittent claudication; the benefits of oral anticoagulant therapy are outweighed by the risk of serious bleeding; the risk of bleeding is probably increased by combined treatment.
Association for Professionals in Infection Control and Epidemiology, Inc.