ACES

ACES

Cardiology
Azithromycin Coronary Events Study. A trial that asked whether Chlamydia pneumoniae infection is causally associated with cardiovascular disease and, if so, whether azithromycin treatment would reduce the risk of subsequent coronary events.

Logistics
Randomised, double-blind, placebo-controlled test; adults with stable coronary heart disease. ACES was sponsored by the National Heart, Lung, & Blood Institute; participants randomised to treatment received 600 mg of azithromycin orally once/week X 1 year, then were followed for a mean of 4 years.

Primary endpoint
Composite—coronary heart disease death, nonfatal myocardial infarction, hospitalisation for unstable angina, coronary revascularisation.
 
Conclusions
No link between cardiovascular disease and Chlamydia pneumoniae; azithromycin treatment doesn’t affect morbidity or mortality.

Medspeak Abbreviation for:
adverse cardiac event
adverse clinical event

Microbiology
Avelox Clinical Experience Study.
A post-marketing study which assessed the safety and efficacy of Avelox (moxifloxacin), a fluoroquinolone.
 
Conclusion
Avelox is useful for managing acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial sinusitis, and community-acquired pneumonia.

Nutrition
An acronym for the major dietary antioxidants—vitamin A (and beta carotene), vitamin C, vitamin E, and selenium. Increased consumption of the ACES group is thought to decrease the effects of ageing and stimulate the immune system.

Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

ACES

Cardiology A clinical trial–Azithromycin & Coronary Events Study Nutrition An acronyn for the major dietary antioxidants–vitamin A and beta carotene, vitamin C, vitamin E, and selenium

McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.