Werner syndrome

(redirected from Adult premature aging syndrome)
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Wer·ner syn·drome

(wĕr'nĕr), [MIM*277700]
a premature aging disorder presenting sclerodermalike skin changes, bilateral juvenile cataracts, progeria, hypogonadism, and diabetes mellitus; autosomal recessive inheritance, caused by mutation in the WRN gene, which encodes a helicase protein on chromosome 8p.

Wer·ner syn·drome

(wĕr'nĕr), [MIM*277700]
a premature aging disorder presenting sclerodermalike skin changes, bilateral juvenile cataracts, progeria, hypogonadism, and diabetes mellitus; autosomal recessive inheritance, caused by mutation in the WRN gene, which encodes a helicase protein on chromosome 8p.
Farlex Partner Medical Dictionary © Farlex 2012

Werner syndrome

(vĕr′nər) or

Werner's syndrome

(-nərz)
n.
An autosomal recessive disorder characterized by short stature and the appearance of premature aging after puberty, with early development of conditions such as cataracts, cardiovascular disease, osteoporosis, and malignancies.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

Werner syndrome

A rare autosomal recessive progeroid syndrome (OMIM:277700) characterised by premature onset of multiple age-related disorders, including atherosclerosis, cancer, type-2 diabetes, ocular cataracts, osteoporosis, and death by age 47, often due to myocardial infarction.

Molecular pathology
Defects of WRN, which encodes a DNA helicase responsible for maintaining genomic integrity, cause Werner syndrome.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

Wer·ner syn·drome

(ver'ner sin'drōm)
A premature aging disorder consisting of sclerodermalike skin changes, bilateral juvenile cataracts, progeria, hypogonadism, and diabetes mellitus; autosomal recessive inheritance, caused by mutation in the WRN gene, which encodes a helicase protein on chromosome 8p.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

Werner,

Otto, German physician, 1879-1936.
Werner disease - hereditary disorder characterized by premature aging. Synonym(s): progeria adultorum; Werner syndrome
Werner syndrome - Synonym(s): Werner disease
Medical Eponyms © Farlex 2012
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