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Related to Adriamycin: Taxol
trademark for preparations of doxorubicin, an antineoplastic antibiotic.
An antineoplastic antibiotic isolated from Streptomyces peucetius; also used in cytogenetics to produce Q-type chromosome bands.
A trademark for the drug doxorubicin.
AdriamycinAn anthracycline antibiotic with antineoplastic activity, which is used to treat haematologic malignancies, especially leukaemias, but also carcinomas and solid tumours (for which it is not particularly effective); its efficacy is hampered by cardiotoxicity that increases as the cumulative dose passes 500 mg/mm3.
Adverse effects Nausea, vomiting, neutropenia; about one-fourth of Adriamycin-treated patients develop late cardiac abnormalities once the cumulative dose passes 450 mg/mm2 including cardiac failure, dysrhythmia and sudden death; post-mortem examination of the heart reveals myocardial fibrosis.