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adrenocortical carcinomaOncology A rare–≤ 2 in 106/yr tumor of the adrenal cortex; average age 46; ♂:♀ ratio 1:2.5 Clinical ± 70% of Pts with AC have endocrine symptoms due to excess secretion of glucocorticoids and/or androgens, less commonly due to excess mineralocorticoids or estrogens Management Surgical resection, mitotane. See Mitotane.
- Adrenocortical cancer
- Stage I
- CA < 5 cms; no spread to periadrenal tissues
- Stage II
- CA > 5 cms; no spread to periadrenal tissues
- Stage III
- CA spread to periadrenal tissues or lymph nodes
- Stage IV
- CA spread to regional tissues or organs, to lymph nodes around adrenal cortex, or metastasized