Adrenocortical Hypertrophy

Adrenocortical Hypertrophy

A rare—less than 2/million population/year—lesion of the adrenal cortex, which has an average age of onset of 46; male:female ratio, 1:2.5.
Clinical findings Most patients with adrenocortical hypertrophy have endocrine symptoms due to excess secretion of glucocorticoids and/or androgens, less commonly due to excess mineralocorticoids or oestrogens.
Management Surgical resection, mitotane therapy
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