adrenergic

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ad·re·ner·gic

(ad-rĕ-ner'jik),

1. Relating to nerve cells or fibers of the autonomic nervous system that use norepinephrine as their neurotransmitter. Compare: cholinergic.

2. Relating to drugs that mimic the actions of the sympathetic nervous system.

[adren- + G. ergon, work]

adrenergic

(ăd′rə-nûr′jĭk)

adj.

1. Activated by or capable of releasing epinephrine or a similar substance, especially in the sympathetic nervous system: adrenergic receptors.

2. Having physiological effects similar to those of epinephrine: an adrenergic amine.

ad′re·ner′gi·cal·ly adv.

Adrenergic

adjective Referring to
(1) Neural activation by catecholamines—e.g., adrenaline/epinephrine, noradrenaline/norepinephrine, dopamine.
(2) Sympathetic nerve fibres that liberate catecholamines into a synapse.
noun Any agent with adrenergic-agonist activity.

adrenergic

adjective Referring to

1. Neural activation by catecholamines–eg, epinephrine, norepinephrine, dopamine. See Biogenic amines, Neurotransmitters, Sympathetic nervous system.

2. Sympathetic nerve fibers that liberate epinephrine or norepinephrine into a synapse noun Any agent with adrenergic–agonist activity.

ad·re·ner·gic

(ad'rĕ-nĕr'jik)

1. Relating to nerve cells or fibers of the autonomic nervous system that employ norepinephrine as their neurotransmitter.
Compare: cholinergic

2. Relating to drugs that mimic the actions of the sympathetic nervous system.
See: alpha (α)-adrenergic receptors, beta (β)-adrenergic receptors

[adren- + G. ergon, work]

adrenergic

Having effects similar to those of ADRENALINE. Drugs with adrenaline-like action are called adrenergic. A nerve which releases noradrenaline (a substance closely related to adrenaline) at its endings to pass on its impulses to other nerves, or to muscle fibres, is described as an adrenergic nerve.

adrenergic

(of nerve endings) secreting ADRENALINE and NORADRENALINE on the arrival of a NERVE IMPULSE. These substances then stimulate the effector nerve fibres in the SYMPATHETIC NERVOUS SYSTEM of many vertebrates in much the same way as ACETYLCHOLINE acts as a transmitter substance in CHOLINERGIC nerve fibres.

Adrenergic

Activated by adrenalin (norepinephrine), loosely applied to the sympathetic nervous system responses.

Mentioned in: Alpha 1 -Adrenergic Blockers, Antihypertensive Drugs

adrenergic

1. Relating to a neuron that is activated or capable of releasing adrenaline (epinephrine).

2. Having an effect similar to adrenaline (epinephrine).

3. Relating to drugs that mimic the effects of the sympathetic nervous system (sympathomimetic drugs).

ad·re·ner·gic

(ad'rĕ-nĕr'jik)

1. Relating to nerve cells or fibers of the autonomic nervous system that use norepinephrine as their neurotransmitter.

2. Relating to drugs that mimic actions of the sympathetic nervous system.

[adren- + G. ergon, work]

References in periodicals archive ?

The [alpha]-2 adrenergic agonists can cause bradycardia, decreased cardiac output, sinoatrial blocks, first and second grade of atrio-ventricular block, atrio-ventricular dissociation, and marked sinus arrhythmias.

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Animal studies support the concept that in humans prenatal exposure to continuous high doses of beta 2 adrenergic agonists can permanently dysregulate signaling from the beta 2 adrenergic receptor.

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As stated earlier, the two major advances in asthma treatment in the past 20 years, inhaled steroids and beta adrenergic agonists, are both prescription-only drugs.

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adrenergic agonists as alternative or adjunctive treatments.

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Acalovschi I, Bodolea C et al [11] in their study on the effects of added alpha adrenergic agonists to spinal anaesthesia with Meperidine showed that the addition of clonidine prolonged the postoperative analgesia (P < 0.001), but was associated with an increased sedation score.

A study on the efficacy of intrathecal clonidine as an adjuvant to bupivacaine in postoperative analgesia

The anaesthetic and analgesic requirement get reduced to much extent by the use of alpha-2 adrenergic agonist dexmedetomidine as an adjuvant, because of its analgesic properties and augmentation of local anaesthetic effects as they cause hyperpolarisation of nerve tissues by alteration of transmembrane potential and ion conductance at locus coeruleus in the brain stem.

A comparative evaluation of ropivacaine hydrochloride and ropivacaine hydrochloride with dexmedetomidine for caudal epidural anaesthesia in paediatric patients undergoing elective infraumbilical surgeries

Most of the clinical studies about the intrathecal [[alpha].sub.2] adrenergic agonist are related to clonidine, acts as an analgesic, a sedative and as a sympatholytic with potent antinociceptive properties.

A randomised, double-blind, placebo-controlled trial comparing dexmedetomidine and clonidine as an adjuvant to intrathecal ropivacaine in lower limb surgery

The complimentary action of local anaesthetics and [alpha]-2 adrenergic agonists accounts for their profound analgesic properties.

A randomised clinical trial comparing the efficacy and safety of ropivacaine 0.75% alone and in combination with dexmedetomidine in epidural anaesthesia for lower limb surgeries

[alpha]-2 adrenergic agonists have both analgesic and sedative properties when used as an adjuvant in regional anaesthesia.

Comparison of 0.5% ropivacaine with dexmedetomidine and 0.5% bupivacaine with dexmedetomidine for epidural anaesthesia in lower abdominal and lower limb surgeries

In addition to ipratropium, they include short-acting [[beta].sub.2] adrenergic agonists like albuterol, and two long-acting inhaled [[beta].sub.2] adrenergic agonists: salmeterol (Serevent) and formoterol (Foradil), which are taken twice a day.

Panel backs once-daily anticholinergic for COPD. (Dyspnea Claim Rejected)

Many clinical studies have been done on intrathecal [alpha]-2 adrenergic agonists are related to clonidine.

Evaluating the efficacy of low dose dexmedetomidine with low dose bupivacaine as an adjuvant for lower limb surgery in elderly and high risk patients